1. Gene
  2. LRRN3 - leucine rich repeat neuronal 3 Gene

LRRN3 - leucine rich repeat neuronal 3 Gene

中文名称:富亮氨酸重复神经元 3

种属: Homo sapiens

同用名: NLRR3; NLRR-3; FIGLER5

基因 ID: 54674 | 基因类型: protein coding

关于 LRRN3

Cytogenetic location: 7q31.1 Genomic coordinates (GRCh38): 7:111,091,127-111,125,454 (from NCBI)

This gene has 5 transcripts (splice variants), 242 orthologues and 25 paralogues. Biased expression in adrenal (RPKM 13.7), brain (RPKM 11.9) and 12 other tissues.

功能概要

预计在突触组装的正调节上游或正调节内起作用。预计是膜的组成部分。预计在细胞外基质和细胞外空间中具有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

LRRN3 基因产物(3)

mRNA Protein Name
NM_001099658.2 NP_001093128.1 leucine-rich repeat neuronal protein 3 precursor
NM_001099660.2 NP_001093130.1 leucine-rich repeat neuronal protein 3 precursor
NM_018334.5 NP_060804.3 leucine-rich repeat neuronal protein 3 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

LRRN3 蛋白结构

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (28 - 68)

LRR_8

LRR_8: Leucine rich repeat (116 - 176)

LRR_8

LRR_8: Leucine rich repeat (213 - 272)

LRR_8

LRR_8: Leucine rich repeat (310 - 370)

I-set

I-set: Immunoglobulin I-set domain (428 - 513)

fn3

fn3: Fibronectin type III domain (526 - 593)

  • 0
  • 200
  • 400
  • 600
  • 708 a.a.
蛋白主名 其他名称

leucine-rich repeat neuronal protein 3

fibronectin type III, immunoglobulin and leucine rich repeat domains 5

重组 LRRN3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77067 LRRN3/NLRR-3 Protein, Human (sf9, His) Q9H3W5 (M1-T628) ≥95%

关联疾病

疾病名称 别名
Vascular Skin Disease

Skin Diseases, Vascular

Skin Vascular Disease

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus LRRN3 MGD MGI:106036
Rattus norvegicus LRRN3 RGD RGD:71066
Felis catus LRRN3 VGNC VGNC:63312
Macaca mulatta LRRN3 VGNC VGNC:81716
Canis familiaris LRRN3 VGNC VGNC:42826
Bos taurus LRRN3 VGNC VGNC:31040
Others LRRN3 NCBI