1. Gene
  2. ST7L - suppression of tumorigenicity 7 like Gene

ST7L - suppression of tumorigenicity 7 like Gene

中文名称:抑制致瘤性 7 样

种属: Homo sapiens

同用名: ST7R; STLR; FAM4B

基因 ID: 54879 | 基因类型: protein coding

关于 ST7L

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:112,517,803-112,619,684 (from NCBI)

This gene has 28 transcripts (splice variants), 210 orthologues and 1 paralogue. Broad expression in testis (RPKM 6.6), skin (RPKM 3.2) and 24 other tissues.

功能概要

该基因通过与染色体 7q31 区域中发现的 ST7 肿瘤抑制基因的相似性得到鉴定。该基因与 WNT2B 基因以尾对尾的方式聚集在已知在多种癌症中被删除和重排的染色体区域中。已经描述了编码许多不同亚型的几种转录变体,但有些尚未完全表征。[RefSeq 提供,2011 年 2 月]

This gene was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized. [provided by RefSeq, Feb 2011]

ST7L 基因产物(5)

mRNA Protein Name
NM_001308264.2 NP_001295193.1 suppressor of tumorigenicity 7 protein-like isoform 7
NM_017744.5 NP_060214.2 suppressor of tumorigenicity 7 protein-like isoform 1
NM_138727.4 NP_620055.1 suppressor of tumorigenicity 7 protein-like isoform 2
NM_138728.3 NP_620056.1 suppressor of tumorigenicity 7 protein-like isoform 3
NM_138729.4 NP_620057.1 suppressor of tumorigenicity 7 protein-like isoform 4

ST7L 蛋白结构

ST7

ST7: ST7 protein (43 - 549)

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  • 575 a.a.
蛋白主名 其他名称

suppressor of tumorigenicity 7 protein-like

ST7-related protein

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ST7L RGD RGD:1359336
Bos taurus ST7L VGNC VGNC:35343
Macaca mulatta ST7L VGNC VGNC:77954
Felis catus ST7L VGNC VGNC:65735
Canis familiaris ST7L VGNC VGNC:46863
Mus musculus ST7L MGD MGI:2386964
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