1. Gene
  2. CYP2W1 - cytochrome P450 family 2 subfamily W member 1 Gene

CYP2W1 - cytochrome P450 family 2 subfamily W member 1 Gene

中文名称:细胞色素 P450 家族 2 亚家族 W 成员 1

种属: Homo sapiens

基因 ID: 54905 | 基因类型: protein coding

关于 CYP2W1

Cytogenetic location: 7p22.3 Genomic coordinates (GRCh38): 7:983,181-989,640 (from NCBI)

This gene has 5 transcripts (splice variants), 107 orthologues and 15 paralogues. Biased expression in skin (RPKM 2.9), duodenum (RPKM 2.7) and 8 other tissues.

功能概要

该基因编码细胞色素 P450 酶超家族的成员。细胞色素 P450 蛋白是单加氧酶,可催化许多涉及药物代谢和胆固醇、类固醇和其他脂质合成的反应。[RefSeq 提供,2008 年 7 月]

This gene encodes a member of the Cytochrome P450 superfamily of Enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and Other lipids. [provided by RefSeq, Jul 2008]

CYP2W1 基因产物(1)

mRNA Protein Name
NM_017781.3 NP_060251.2 cytochrome P450 2W1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables all-trans retinal binding IDA
IDA: 通过直接分析推断
26936974 GOA
enables all-trans-retinol binding IDA
IDA: 通过直接分析推断
26936974 GOA
enables retinoic acid 4-hydroxylase activity IDA
IDA: 通过直接分析推断
26936974 GOA
enables retinoic acid binding IDA
IDA: 通过直接分析推断
26936974 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in aflatoxin metabolic process IDA
IDA: 通过直接分析推断
16551781 GOA
involved in phospholipid metabolic process IDA
IDA: 通过直接分析推断
22591743 GOA
involved in retinoic acid catabolic process IDA
IDA: 通过直接分析推断
26936974 GOA
involved in xenobiotic metabolic process IDA
IDA: 通过直接分析推断
16551781 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
20805301 GOA
located in endoplasmic reticulum lumen IDA
IDA: 通过直接分析推断
20805301 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CYP2W1 蛋白结构

p450

p450: Cytochrome P450 (32 - 483)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 490 a.a.
蛋白主名 其他名称

cytochrome P450 2W1

CYPIIW1

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CYP2W1 VGNC VGNC:81300
Felis catus CYP2W1 VGNC VGNC:103323
Canis familiaris CYP2W1 VGNC VGNC:50358
Rattus norvegicus CYP2W1 RGD RGD:1305193
Bos taurus CYP2W1 VGNC VGNC:110263
Mus musculus CYP2W1 MGD MGI:3616076