2. Gene
  3. SUSD4 - sushi domain containing 4 Gene

SUSD4 - sushi domain containing 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 Sushi 域 4

种属: Homo sapiens

同用名: PRO222

基因 ID: 55061 | 基因类型: protein coding

关于 SUSD4

Cytogenetic location: 1q41 Genomic coordinates (GRCh38): 1:223,220,831-223,365,235 (from NCBI)

This gene has 17 transcripts (splice variants), 145 orthologues and 39 paralogues. Biased expression in esophagus (RPKM 11.1), ovary (RPKM 10.5) and 13 other tissues.

功能概要

参与补体激活的负调节、替代途径和补体激活的负调节、经典途径。预测位于细胞外区域。预计是膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Involved in negative regulation of complement activation, alternative pathway and negative regulation of complement activation, classical pathway. Predicted to be located in extracellular region. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

SUSD4 基因产物(3)

mRNA Protein Name
NM_001037175.3 NP_001032252.1 sushi domain-containing protein 4 isoform b precursor
NM_001410929.1 NP_001397858.1 sushi domain-containing protein 4 isoform c
NM_017982.4 NP_060452.3 sushi domain-containing protein 4 isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of complement activation, alternative pathway IDA
IDA: 通过直接分析推断
23482636 GOA
involved in negative regulation of complement activation, classical pathway IDA
IDA: 通过直接分析推断
23482636 GOA
involved in regulation of complement activation IDA
IDA: 通过直接分析推断
23482636 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SUSD4 蛋白结构

Sushi

Sushi: Sushi repeat (SCR repeat) (57 - 104)

Sushi

Sushi: Sushi repeat (SCR repeat) (122 - 177)

Sushi

Sushi: Sushi repeat (SCR repeat) (180 - 237)

Sushi

Sushi: Sushi repeat (SCR repeat) (243 - 297)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 490 a.a.
蛋白主名 其他名称

sushi domain-containing protein 4

YHGM196

重组 SUSD4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77217 SUSD4 Protein, Human (HEK293, Fc) Q5VX71-3 (F42-F290) ≥95%

关联疾病

疾病名称 别名
Chromosome 1q41-Q42 Deletion Syndrome

1q41-Q42 Microdeletion Syndrome

1q41q42 Microdeletion Syndrome

Holoprosencephaly 10, Included

Hpe10, Included

1q41-Q42 Deletion Syndrome

Deletion 1q41-Q42

Monosomy 1q41-Q42

Del(1)(Q41q42)

Monosomy 1q41q42

Chromosome Deletion Syndrome 1q41-Q42

Holoprosencephaly 10
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14049 SUSD4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SUSD4 MGD MGI:2138351
Felis catus SUSD4 VGNC VGNC:65855
Bos taurus SUSD4 VGNC VGNC:35489
Canis familiaris SUSD4 VGNC VGNC:49817
Rattus norvegicus SUSD4 RGD RGD:1564043
Macaca mulatta SUSD4 VGNC VGNC:78211
Others SUSD4 NCBI
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