SAGE1 - sarcoma antigen 1 Gene

中文名称：肉瘤抗原 1

种属: Homo sapiens

同用名: CT14; SAGE

关于 SAGE1

功能概要

该基因属于一类在肿瘤中被激活的基因。这些基因在不同组织学类型的肿瘤中表达，但在正常组织中不表达，除了生精细胞和一些胎盘。由这些基因编码的蛋白质似乎具有严格的肿瘤特异性，因此可能是癌症免疫疗法的极好抗原来源。该基因在肉瘤中表达。[RefSeq 提供，2008 年 7 月]

This gene belongs to a class of genes that are activated in tumors. These genes are expressed in tumors of different histologic types but not in normal tissues, except for spermatogenic cells and, for some, placenta. The proteins encoded by these genes appear to be strictly tumor specific, and hence may be excellent sources of antigens for Cancer Immunotherapy. This gene is expressed in sarcomas. [provided by RefSeq, Jul 2008]