2. Gene
  3. KIF16B - kinesin family member 16B Gene

KIF16B - kinesin family member 16B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：驱动蛋白家族成员 16B

种属: Homo sapiens

同用名: SNX23; C20orf23; KISC20ORF

基因 ID: 55614 | 基因类型: protein coding

关于 KIF16B

Cytogenetic location: 20p12.1 Genomic coordinates (GRCh38): 20:16,272,104-16,573,448 (from NCBI)

This gene has 6 transcripts (splice variants), 166 orthologues and 41 paralogues. Ubiquitous expression in adrenal (RPKM 10.5), colon (RPKM 7.0) and 24 other tissues.

功能概要

该基因编码的蛋白质是一种驱动蛋白样蛋白，可能参与细胞内运输。已发现该基因的三个转录变体编码不同的亚型。[RefSeq 提供，2010 年 12 月]

The protein encoded by this gene is a kinesin-like protein that may be involved in intracellular trafficking. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

KIF16B 基因产物(4)

mRNA Protein Name
NM_001199865.2 NP_001186794.1 kinesin-like protein KIF16B isoform 3
NM_001199866.2 NP_001186795.1 kinesin-like protein KIF16B isoform 1
NM_001410853.1 NP_001397782.1 kinesin-like protein KIF16B isoform 4
NM_024704.5 NP_078980.3 kinesin-like protein KIF16B isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
IDA: 通过直接分析推断
15882625 GOA
enables phosphatidylinositol-3,4-bisphosphate binding IDA
IDA: 通过直接分析推断
15882625 GOA
enables phosphatidylinositol-3,5-bisphosphate binding IDA
IDA: 通过直接分析推断
17641687 GOA
enables phosphatidylinositol-3-phosphate binding IDA
IDA: 通过直接分析推断
15882625 GOA
enables plus-end-directed microtubule motor activity IDA
IDA: 通过直接分析推断
15882625 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in early endosome to late endosome transport IMP
IMP: 通过突变表型推断
15882625 GOA
involved in epidermal growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
15882625 GOA
involved in receptor catabolic process IMP
IMP: 通过突变表型推断
15882625 GOA
involved in regulation of receptor recycling IMP
IMP: 通过突变表型推断
15882625 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
18445686 GOA
located in early endosome IDA
IDA: 通过直接分析推断
15882625 GOA
located in endosome IDA
IDA: 通过直接分析推断
17641687 GOA
located in spindle IDA
IDA: 通过直接分析推断
18445686 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

KIF16B 蛋白结构

Kinesin

Kinesin: Kinesin motor domain (9 - 358)

FHA

FHA: FHA domain (480 - 544)

PX

PX: PX domain (1197 - 1272)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1317 a.a.
蛋白主名 其他名称

kinesin-like protein KIF16B

kinesin motor protein

关联疾病

疾病名称 别名
Congenital Fibrosis Of The Extraocular Muscles

Congenital Fibrosis Of Extraocular Muscles

Cfeom

Feom

Congenital External Ophthalmoplegia

Congenital Fibrosis Syndrome

General Fibrosis Syndrome
Megabladder, Congenital

MGBL

Congenital Megabladder
Small Intestine Neuroendocrine Neoplasm

Small Intestine Neuroendocrine Tumor

Neuroendocrine Tumor Of The Small Intestine

Net Of The Small Intestine

Neuroendocrine Neoplasm Of The Small Intestine

Neuroendocrine Tumor Of Small Bowel

Small Intestinal Neuroendocrine Neoplasm
Combined Oxidative Phosphorylation Deficiency 20

COXPD20

Combined Oxidative Phosphorylation Defect Type 20

Oxidative Phosphorylation Deficiency, Combined, Type 20
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07265 KIF16B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus KIF16B VGNC VGNC:63105
Macaca mulatta KIF16B VGNC VGNC:73839
Rattus norvegicus KIF16B RGD RGD:1310146
Mus musculus KIF16B MGD MGI:1098240
Bos taurus KIF16B VGNC VGNC:30585
Canis familiaris KIF16B VGNC VGNC:42385
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