1. Gene
  2. CNDP2 - carnosine dipeptidase 2 Gene

CNDP2 - carnosine dipeptidase 2 Gene

中文名称:肌肽二肽酶 2

种属: Homo sapiens

同用名: CN2; CPGL; PEPA; HsT2298; HEL-S-13

基因 ID: 55748 | 基因类型: protein coding

关于 CNDP2

Cytogenetic location: 18q22.3 Genomic coordinates (GRCh38): 18:74,496,363-74,523,454 (from NCBI)

This gene has 29 transcripts (splice variants), 223 orthologues and 3 paralogues. Ubiquitous expression in kidney (RPKM 58.4), small intestine (RPKM 41.5) and 24 other tissues.

功能概要

CNDP2,也称为组织肌肽酶和肽酶 A (EC 3.4.13.18) ,是一种非特异性二肽酶,而不是选择性肌肽酶 (Teufel 等人,2003 [PubMed 12473676]) 。[OMIM 提供,2008 年 3 月]

CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008]

CNDP2 基因产物(6)

mRNA Protein Name
NM_001168499.2 NP_001161971.1 cytosolic non-specific dipeptidase isoform 2
NM_001370248.1 NP_001357177.1 cytosolic non-specific dipeptidase isoform 1
NM_001370249.1 NP_001357178.1 cytosolic non-specific dipeptidase isoform 1
NM_001370250.1 NP_001357179.1 cytosolic non-specific dipeptidase isoform 1
NM_001370254.1 NP_001357183.1 cytosolic non-specific dipeptidase isoform 3
NM_018235.3 NP_060705.2 cytosolic non-specific dipeptidase isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
33961781 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CNDP2 蛋白结构

Peptidase_M20

Peptidase_M20: Peptidase family M20/M25/M40 (95 - 468)

M20_dimer

M20_dimer: Peptidase dimerisation domain (208 - 366)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 475 a.a.
蛋白主名 其他名称

cytosolic non-specific dipeptidase

CNDP dipeptidase 2 (metallopeptidase M20 family)

重组 CNDP2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76837 CNDP2 Protein, Human (sf9, His) Q96KP4-1 (M1-D475) ≥95%

关联疾病

疾病名称 别名
Penile Cancer

Penis Carcinoma

Carcinoma Of Penis

Penile Neoplasm

Penile Carcinoma

Penile Neoplasms

Malignant Neoplasm Of Penis

Ca Penis

Malignant Neoplasm Of Body Of Penis

Malignant Penile Tumor

Penile Ca

Intermediate Malignant Teratoma

Malignant Teratoma, Intermediate

Intermediate Immature Teratoma

Pyriform Sinus Cancer

Malignant Neoplasm Of Pyriform Fossa

Malignant Neoplasm Of The Pyriform Fossa

Malignant Tumor Of Pyriform Fossa

Supraglottis Neoplasm

Neoplasm Of Supraglottis

Supraglottic Tumor

Penile Disease

Penile Diseases

Trachea Carcinoma

Pancoast Tumor

Carcinoma Of The Trachea

Pancoast'S Tumor

Malignant Superior Sulcus Tumor

Malignant Superior Sulcus Tumour

Pancoast Tumour

Pancoast'S Syndrome

Pancoast'S Tumour

Pulmonary Sulcus Tumor

Pulmonary Sulcus Tumour

Superior Pulmonary Sulcus Syndrome

Pancoast Syndrome

Penile Benign Neoplasm

Neoplasm Of Penis

Penile Tumor

Cancer Of Penis

Carcinoma Of Penis

Malignant Neoplasm Of Penis, Unspecified

Malignant Neoplasm Of Penis, Part Unspecified

Malignant Tumour Of Penis

Penile Cancer

Primary Malignant Neoplasm Of Penis

Malignant Neoplasm Of Skin Of Penis Nos

Crigler-Najjar Syndrome, Type I

Crigler-Najjar Syndrome

Crigler-Najjar Syndrome Type 1

Bilirubin Udp Glucuronyl Transferase Deficiency

Crigler Najjar Syndrome

Crigler Najjar Syndrome, Type 1

Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency

Bilirubin-Ugt Deficiency

Hyperbilirubinemia, Crigler-Najjar Type I

Hblrcn1

Familial Nonhemolytic Unconjugated Hyperbilirubinemia

Hereditary Unconjugated Hyperbilirubinemia

Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency Type 1

Bilirubin-Ugt Deficiency Type 1

Crigler-Najjar Syndrome 1

CN1

Cn-I

Crigler-Najjar Syndrome Type I

Hereditary Unconjugated Hyperbilirubinaemia

Ugt Deficiency

Bilirubin Glucuronosyltransferase Deficiency

Crigler-Najjar Disease Or Syndrome

Deficiency Of Glucuronosyltransferase

Glucuronyl Transferase Deficiency

Glucuronyltransferase Deficiency

Udp Glucuronyl Transferase Deficiency

Cns - [Crigler-Najjar Syndrome]

Congenital Familial Nonhemolytic Jaundice

Tolosa-Hunt Syndrome

Painful Ophthalmoplegia

Tolosa Hunt Syndrome

Nonspecific Inflammation Of The Cavernous Sinus Or Superior Orbital Fissure

Ths

Ophthalmoplegia, Painful

Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach

Gilbert Syndrome

Gilbert Disease

Gilbert'S Disease

Gilbert'S Syndrome

Cholemia, Familial

Familial Nonhemolytic Jaundice

Meulengracht Syndrome

Gilbert Syndrome, Susceptibility To

Hyperbilirubinemia, Gilbert Type

Hblrg

Hyperbilirubinemia, Arias Type

Hyperbilirubinemia I

Constitutional Hyperbilirubinemia

Gilbert-Meulengracht Syndrome

Hereditary Nonhemolytic Jaundice

Hyperbilirubinemia Arias Type

Hyperbilirubinemia Type 1

Constitutional Liver Dysfunction

Gilbert-Lereboullet Syndrome

Hyperbilirubinemia 1

Unconjugated Benign Bilirubinemia

GILBS

Gilberts Syndrome

Familial Nonhaemolytic Jaundice

Constitutional Hyperbilirubinaemia

Hereditary Nonhaemolytic Bilirubinaemia

Familial Nonhaemolytic Bilirubinaemia

Idiopathic Hyperbilirubinaemia

Icterus Intermittens Juvenilis

Chronic Intermittent Juvenile Jaundice

Low-Grade Chronic Hyperbilirubinaemia Syndrome

Benign Unconjugated Bilirubinaemia Syndrome

Hereditary Nonhaemolytic Jaundice

Idiopathic Unconjugated Hyperbilirubinaemia

Gilbert--Lereboullet Syndrome

Constitutional Hepatic Dysfunction

Meulengracht Icterus

Cholaemia Familiaris Simplex

Familial Cholaemia

Congenital Familial Cholaemia

Physiologic Cholaemia

Hyperbilirubinaemia Type 1

Gilbert Cholaemia

Bilirubin Metabolic Disorder

Hyperbilirubinemia

Hereditary Hyperbilirubinemia

Hyperbilirubinemia, Hereditary

Hyperbilirubinaemia

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus CNDP2 VGNC VGNC:61009
Mus musculus CNDP2 MGD MGI:1913304
Canis familiaris CNDP2 VGNC VGNC:39392
Macaca mulatta CNDP2 VGNC VGNC:71337
Bos taurus CNDP2 VGNC VGNC:27494
Rattus norvegicus CNDP2 RGD RGD:1305827
Others CNDP2 NCBI