2. Gene
  3. IL26 - interleukin 26 Gene

IL26 - interleukin 26 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：白细胞介素 26

种属: Homo sapiens

同用名: AK155; IL-26

基因 ID: 55801 | 基因类型: protein coding

关于 IL26

Cytogenetic location: 12q15 Genomic coordinates (GRCh38): 12:68,201,349-68,225,810 (from NCBI)

This gene has 1 transcript (splice variant), 70 orthologues and 4 paralogues. Low expression observed in reference dataset.

功能概要

该基因通过其在疱疹病毒 samimiri 转化的 T 细胞中的特异性过表达而被鉴定。编码的蛋白质是 IL10 细胞因子家族的成员。它是一种分泌蛋白，可以作为同型二聚体发挥作用。这种蛋白质被认为有助于 T 细胞在被 samimiri 疱疹病毒感染后的转化表型。[RefSeq 提供，2008 年 7 月]

This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after Infection by herpesvirus samimiri. [provided by RefSeq, Jul 2008]

IL26 基因产物(1)

mRNA Protein Name
NM_018402.2 NP_060872.1 interleukin-26 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine activity IDA
IDA: 通过直接分析推断
18483078 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of epithelial cell proliferation IDA
IDA: 通过直接分析推断
18483078 GOA
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
18483078 GOA
involved in positive regulation of cytokine production IDA
IDA: 通过直接分析推断
18483078 GOA
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
18483078 GOA
involved in positive regulation of receptor signaling pathway via JAK-STAT IDA
IDA: 通过直接分析推断
18483078 GOA
involved in positive regulation of stress-activated MAPK cascade IDA
IDA: 通过直接分析推断
18483078 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18483078 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
18483078 GOA
located in extracellular space IDA
IDA: 通过直接分析推断
18483078 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

IL26 蛋白结构

IL10

IL10: Interleukin 10 (8 - 164)

  • 0
  • 100
  • 171 a.a.
蛋白主名 其他名称

interleukin-26

重组 IL26 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700117AF Animal-Free IL-26/AK155 Protein, Human (His) Q9NPH9 (K22-Q171) ≥95%

IL26 抗体

目录号 产品名 应用 反应物种
HY-P83270 IL-26 Antibody (YA3015) WB, IHC-P, IP Human

关联疾病

疾病名称 别名
Crohn'S Disease

Crohn Disease

Pediatric Crohn'S Disease

Regional Enteritis

Crohn'S Disease Of Large Bowel

Granulomatous Colitis

Enteritis, Granulomatous

Enteritis

Crohn'S Disease Of Colon

Colitis, Granulomatous

Crohn'S Enteritis

Enteritis, Regional

Ileitis

Adenoviral Enteritis

Acute Gastroenteropathy Due To Norwalk Agent

Viral Gastroenteritis Due To Norwalk Agent

Winter Vomiting

Epidemic Winter Vomiting Disease

Small Round Structured Virus Enteritis

Epidemic Vomiting Syndrome

Epidemic Vomiting

Epidemic Nausea

Epidemic Viral Gastroenteritis Due To Norwalk Virus

Noroviral Enteritis

Crohn Disease Nos

Crohns

Cd - [Crohn'S Disease]

Regional Enteritis Of Bowel

Crohn'S Regional Enteritis

Cobble-Stone Appearance Of Intestine

Intestinal Ulcer And Erosion Due To Crohn Disease

Granulomatous Enteritis
Hidradenitis Suppurativa

Acne Inversa

Suppurative Hidradenitis

Acne Inversa, Familial

Apocrinitis

Hidradenitides, Suppurative

Hidradenitis, Suppurative

Suppurative Hidradenitides

Inverse Acne
Hidradenitis

Hydradenitis
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory
Psoriasis 12

PSORS12

Psoriasis Susceptibility 12

Psoriasis 12, Susceptibility To
Rheumatoid Arthritis

RA

Arthritis, Rheumatoid

Rheumatoid Arthritis, Susceptibility To

Arthritis Or Polyarthritis, Rheumatic

Atrophic Arthritis

Rheumatism Arthritis

Rheumatoid Polyarthritis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06745 IL26 Human Pre-designed siRNA Set A Pre-designed Sets / 否
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