2. Gene
  3. EAPP - E2F associated phosphoprotein Gene

EAPP - E2F associated phosphoprotein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：E2F 相关磷蛋白

种属: Homo sapiens

同用名: BM036; C14orf11

基因 ID: 55837 | 基因类型: protein coding

关于 EAPP

Cytogenetic location: 14q13.1 Genomic coordinates (GRCh38): 14:34,515,938-34,539,701 (from NCBI)

This gene has 4 transcripts (splice variants) and 215 orthologues. Ubiquitous expression in bone marrow (RPKM 22.0), colon (RPKM 18.0) and 25 other tissues.

功能概要

该基因编码的磷蛋白与 E2F 蛋白家族的几个成员相互作用。该蛋白质定位于细胞核，并且存在于除有丝分裂期间之外的整个细胞周期中。它的功能是调节 E2F 调节的转录并刺激增殖。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 1 月]

This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

EAPP 基因产物(2)

mRNA Protein Name
NM_001318916.2 NP_001305845.1 E2F-associated phosphoprotein isoform 2
NM_018453.4 NP_060923.2 E2F-associated phosphoprotein isoform 1

EAPP 蛋白结构

Eapp_C

Eapp_C: E2F-associated phosphoprotein (138 - 283)

  • 0
  • 100
  • 200
  • 285 a.a.
蛋白主名 其他名称

E2F-associated phosphoprotein

EAPP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
EAPP Q56P03 AAR2 Homo sapiens Q9Y312
Anti Tag CoIP
33961781
种属内
EAPP Q56P03 AAR2 Homo sapiens Q9Y312
Anti Tag CoIP
28514442
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Holoprosencephaly 8

HPE8

Holoprosencephaly-8
Spastic Hemiplegia

Spastic Hemiplegic Cerebral Palsy

Hemiplegic Cerebral Palsy

Congenital Hemiplegia

Hemiplegic Infantile Cerebral Palsy

Cerebral Palsy Spastic Hemiplegic

Spastic Hemiplegia Cerebral Palsy

Hemiplegia, Spastic
Holoprosencephaly

Holoprosencephaly Sequence

Hpe

Hpe - [Holoprosencephaly]
Cartilage Cancer

Chondrogenic Neoplasm
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-149209 LL-K8-22 99.76% 否
HY-RS04121 EAPP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus EAPP MGD MGI:1913516
Macaca mulatta EAPP VGNC VGNC:108295
Felis catus EAPP VGNC VGNC:80981
Rattus norvegicus EAPP RGD RGD:1309624
Bos taurus EAPP VGNC VGNC:28296
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