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  2. LTB4R2 - leukotriene B4 receptor 2 Gene

LTB4R2 - leukotriene B4 receptor 2 Gene

中文名称:白三烯 B4 受体 2

种属: Homo sapiens

同用名: BLT2; NOP9; BLTR2; JULF2; KPG_004; LTB4-R2; LTB4-R 2

基因 ID: 56413 | 基因类型: protein coding

关于 LTB4R2

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:24,310,140-24,312,038 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 238 orthologues and 17 paralogues. Broad expression in skin (RPKM 12.7), spleen (RPKM 9.3) and 21 other tissues.

功能概要

预计可启用 G 蛋白偶联肽受体活性和白三烯 B4 受体活性。预计参与炎症反应和神经肽信号通路。预计在角质形成细胞迁移和信号转导的上游或内部起作用。位于核质和质膜中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled peptide receptor activity and leukotriene B4 receptor activity. Predicted to be involved in inflammatory response and neuropeptide signaling pathway. Predicted to act upstream of or within keratinocyte migration and signal transduction. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LTB4R2 基因产物(2)

mRNA Protein Name
NM_001164692.3 NP_001158164.1 leukotriene B4 receptor 2
NM_019839.5 NP_062813.2 leukotriene B4 receptor 2
蛋白主名 其他名称

leukotriene B4 receptor 2

LTB4 receptor JULF2

关联疾病

疾病名称 别名
Psoriasis 5

PSORS5

Psoriasis Susceptibility 5

Psoriasis 5, Susceptibility To

Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus

Persistent Mild Asthma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus LTB4R2 VGNC VGNC:31070
Mus musculus LTB4R2 MGD MGI:1888501
Rattus norvegicus LTB4R2 RGD RGD:621029
Macaca mulatta LTB4R2 VGNC VGNC:74314