PSG6 - pregnancy specific beta-1-glycoprotein 6 Gene

中文名称：妊娠特异性 β-1-糖蛋白 6

种属: Homo sapiens

同用名: PSG10; PSGGB; PSBG-6; PSBG-10; PSBG-12

关于 PSG6

功能概要

该基因是妊娠特异性糖蛋白 (PSG) 基因家族的成员。 PSG 基因是免疫球蛋白样基因的癌胚抗原 (CEA) 家族的一个亚组，发现于 19q13.1-q13.2 端粒到另一个 CEA 相关基因簇的基因簇中。 PSG 基因由胎盘滋养细胞表达，并在怀孕期间释放到母体循环中，被认为是维持正常妊娠所必需的。该基因编码的蛋白质含有与细胞粘附和识别相关的 Arg-Gly-Asp 三肽。可变剪接导致多种转录本变体和蛋白质同种型。[RefSeq 提供，2012 年 7 月]

This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The protein encoded by this gene contains the Arg-Gly-Asp tripeptide associated with cellular adhesion and recognition. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]