1. Gene
  2. BDH2 - 3-hydroxybutyrate dehydrogenase 2 Gene

BDH2 - 3-hydroxybutyrate dehydrogenase 2 Gene

中文名称:3-羟基丁酸脱氢酶 2

种属: Homo sapiens

同用名: DHRS6; EFA6R; SDR15C1; UCPA-OR; UNQ6308; PRO20933

基因 ID: 56898 | 基因类型: protein coding

关于 BDH2

This gene has 9 transcripts (splice variants) and 201 orthologues. Broad expression in kidney (RPKM 50.7), duodenum (RPKM 25.0) and 23 other tissues.

功能概要

启用 3-羟基丁酸脱氢酶活性和 NAD 结合活性。参与上皮细胞分化和脂肪酸 β-氧化。位于胞质溶胶中。 [由基因组资源联盟提供,2022 年 4 月]

Enables 3-hydroxybutyrate dehydrogenase activity and NAD binding activity. Involved in epithelial cell differentiation and fatty acid beta-oxidation. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

BDH2 基因产物(1)

mRNA Protein Name
NM_020139.4 NP_064524.3 dehydrogenase/reductase SDR family member 6
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3-hydroxybutyrate dehydrogenase activity IDA
IDA: 通过直接分析推断
16380372 GOA
enables NAD binding IDA
IDA: 通过直接分析推断
16380372 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epithelial cell differentiation IDA
IDA: 通过直接分析推断
21492153 GOA
involved in fatty acid beta-oxidation IDA
IDA: 通过直接分析推断
16380372 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16380372 GOA
NOT located in mitochondrion IDA
IDA: 通过直接分析推断
16380372 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

BDH2 蛋白结构

adh_short_C2

adh_short_C2: Enoyl-(Acyl carrier protein) reductase (15 - 243)

  • 0
  • 100
  • 200
  • 245 a.a.
蛋白主名 其他名称

dehydrogenase/reductase SDR family member 6

3-hydroxybutyrate dehydrogenase type 2

(R)-beta-hydroxybutyrate dehydrogenase

重组 BDH2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7659 BDH2 Protein, Human (His) AAH01953.1 (M1-L245) ≥95%

关联疾病

疾病名称 别名
Alpha-Methylacetoacetic Aciduria

Beta-Ketothiolase Deficiency

3-Ketothiolase Deficiency

3-Oxothiolase Deficiency

Mitochondrial Acetoacetyl-Coa Thiolase Deficiency

Alpha-Methylacetoaceticaciduria

Mat Deficiency

T2 Deficiency

2-Methyl-3-Hydroxybutyricacidemia

Beta Ketothiolase Deficiency

Pseudo-Zellweger Syndrome

2-Methyl-3-Hydroxybutyric Acidemia

3-Ktd Deficiency

Peroxisomal Thiolase Deficiency

2-Methylacetoacetyl-Coenzyme A Thiolase Deficiency

3-Alpha-Oxothiolase Deficiency

Methylacetoacetyl-Coenzyme A Thiolase Deficiency

Mitochondrial 2-Methylacetoacetyl-Coa Thiolase Deficiency - Potassium Stimulated

Β-Ketothiolase Deficiency

Alpha Methylacetoacetic Aciduria

Alpha-Methyl-Acetoacetyl-Coa Thiolase Deficiency

Mitochondrial Acetoacetyl-Coenzyme A Thiolase Deficiency

3KTD

Aciduria, Alpha-Methylacetoacetic

Deficiency Of Acetyl-Coa Acetyltransferase

Deficiency Of Acetyl-Coa Acyltransferase

Hepatic Methionine Adenosyltransferase Deficiency

Bifunctional Peroxisomal Enzyme Deficiency

Alcohol Dependence

Alcoholism

Alcohol Dependence, Susceptibility To

Alcohol Dependence, Protection Against

Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against

Alcoholism, Susceptibility To

Alcoholic Intoxication, Chronic

Pharyngeal Neoplasms

Chronic Alcoholism

Dipsomania

Alcohol Addiction

Ethanol Dependence

Chronic Ethanolism

Chronic Alcoholic Disease Nos

Alcoholic Disease Nos

Alcoholic

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus BDH2 VGNC VGNC:26458
Canis familiaris BDH2 VGNC VGNC:38423
Felis catus BDH2 VGNC VGNC:60097
Rattus norvegicus BDH2 RGD RGD:1309898
Mus musculus BDH2 MGD MGI:1917022
Macaca mulatta BDH2 VGNC VGNC:70161
Others BDH2 NCBI
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