2. Gene
  3. NIT2 - nitrilase family member 2 Gene

NIT2 - nitrilase family member 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：腈水解酶家族成员 2

种属: Homo sapiens

同用名: HEL-S-8a

基因 ID: 56954 | 基因类型: protein coding

关于 NIT2

Cytogenetic location: 3q12.2 Genomic coordinates (GRCh38): 3:100,334,757-100,361,635 (from NCBI)

This gene has 7 transcripts (splice variants), 215 orthologues and 2 paralogues. Ubiquitous expression in kidney (RPKM 49.7), liver (RPKM 37.5) and 25 other tissues.

功能概要

启用 omega-amidase 活性。参与天冬酰胺代谢过程；谷氨酰胺代谢过程；和草酰乙酸代谢过程。位于中心体和细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables omega-amidase activity. Involved in asparagine metabolic process; glutamine metabolic process; and oxaloacetate metabolic process. Located in centrosome and cytosol. [provided by Alliance of Genome Resources, Apr 2022]

NIT2 基因产物(1)

mRNA Protein Name
NM_020202.5 NP_064587.1 omega-amidase NIT2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables omega-amidase activity IDA
IDA: 通过直接分析推断
22674578 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in asparagine metabolic process IDA
IDA: 通过直接分析推断
22674578 GOA
involved in glutamine metabolic process IDA
IDA: 通过直接分析推断
22674578 GOA
involved in oxaloacetate metabolic process IDA
IDA: 通过直接分析推断
22674578 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NIT2 蛋白结构

CN_hydrolase

CN_hydrolase: Carbon-nitrogen hydrolase (5 - 177)

  • 0
  • 100
  • 200
  • 276 a.a.
蛋白主名 其他名称

omega-amidase NIT2

Nit protein 2

关联疾病

疾病名称 别名
Histidinemia

Histidine Ammonia-Lyase Deficiency

Hal Deficiency

Histidase Deficiency

His Deficiency

Histidinuria

Hyperhistidinemia

HISTID

Histidinuria Renal Tubular Defect
Atrial Septal Defect 4

ASD4

Atrial Heart Septal Defect 4

Septal Defect, Atrial, Type 4
Histidine Metabolism Disease

Disturbances Of Histidine Metabolism

Disorder Of Histidine Metabolism

Disturbance Of Histidine Metabolism
Alkaptonuria

Homogentisic Acid Oxidase Deficiency

Alcaptonuria

AKU

Deficiency Of Homogentisicase

Homogentisate 1,2-Dioxygenase Deficiency

Alkaptonuric Ochronosis

Homogentisic Acidura

Ochronosis, Hereditary

Hereditary Ochronosis

Ochronosis

Homogentisicaciduria

Deficiency Of Homogentisate Oxygenase
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09311 NIT2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus NIT2 MGD MGI:1261838
Felis catus NIT2 VGNC VGNC:102789
Canis familiaris NIT2 VGNC VGNC:43823
Macaca mulatta NIT2 VGNC VGNC:75281
Bos taurus NIT2 VGNC VGNC:32090
Rattus norvegicus NIT2 RGD RGD:1310494
Others NIT2 NCBI
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