2. Gene
  3. RCN3 - reticulocalbin 3 Gene

RCN3 - reticulocalbin 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：网状局部蛋白 3

种属: Homo sapiens

同用名: RLP49

基因 ID: 57333 | 基因类型: protein coding

关于 RCN3

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:49,528,003-49,543,633 (from NCBI)

This gene has 5 transcripts (splice variants), 105 orthologues and 4 paralogues. Ubiquitous expression in fat (RPKM 12.8), placenta (RPKM 11.9) and 24 other tissues.

功能概要

启用钙离子结合活性。参与多个过程，包括胶原蛋白的生物合成过程；肽酶活性的正调节；和调节蛋白激酶 B 信号。位于内质网。 [由基因组资源联盟提供，2022 年 4 月]

Enables calcium ion binding activity. Involved in several processes, including collagen biosynthetic process; positive regulation of peptidase activity; and regulation of protein kinase B signaling. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

RCN3 基因产物(1)

mRNA Protein Name
NM_020650.3 NP_065701.2 reticulocalbin-3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
16433634 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in collagen biosynthetic process IMP
IMP: 通过突变表型推断
28939891 GOA
involved in positive regulation of peptidase activity IMP
IMP: 通过突变表型推断
28939891 GOA
involved in protein secretion IMP
IMP: 通过突变表型推断
16433634 GOA
involved in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
28939891 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
16433634 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RCN3 蛋白结构

EF-hand_7

EF-hand_7: EF-hand domain pair (80 - 141)

EF-hand_5

EF-hand_5: EF hand (207 - 226)

EF-hand_8

EF-hand_8: EF-hand domain pair (281 - 302)

  • 0
  • 100
  • 200
  • 300
  • 328 a.a.
蛋白主名 其他名称

reticulocalbin-3

EF-hand calcium-binding protein RLP49

重组 RCN3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71253 RCN3 Protein, Human (HEK293, His) Q96D15 (K21-L328) ≥95%

关联疾病

疾病名称 别名
Myopathy, Distal, 3

MPD3

Distal Muscular Dystrophy 3

Distal Myopathy Type 3

Myopathy, Distal 3

Distal Myopathy 3

Finnish Upper Limb-Onset Distal Myopathy
Neonatal Respiratory Failure

Respiratory Failure Of Newborn

Inadequate Pulmonary Ventilation Of Newborn

Newborn Lung Insufficiency

Newborn Pulmonary Function Inadequate

Newborn Pulmonary Insufficiency

Newborn Respiration Failure

Newborn Respiratory Insufficiency

Respiratory Insufficiency Syndrome Of Newborn
Enchondromatosis, Multiple, Ollier Type

Ollier Disease

Enchondromatosis

Dyschondroplasia

Osteochondromatosis

Multiple Cartilaginous Enchondroses

Multiple Enchondromatosis

Enchondromatosis With Haemangiomata

Enchondromatosis, Multiple

Kast'S Syndrome

Ollier'S Syndrome

Enchondromatosis Multiple

ENCHOM

Maffucci Disease

Olliers Disease

Hereditary Multiple Exostoses

Chondromatosis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11790 RCN3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus RCN3 VGNC VGNC:33833
Canis familiaris RCN3 VGNC VGNC:45445
Mus musculus RCN3 MGD MGI:1277122
Rattus norvegicus RCN3 RGD RGD:1359365
Others RCN3 NCBI
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