2. Gene
  3. LRFN2 - leucine rich repeat and fibronectin type III domain containing 2 Gene

LRFN2 - leucine rich repeat and fibronectin type III domain containing 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含富亮氨酸的重复序列和纤连蛋白 III 型结构域， 2

种属: Homo sapiens

同用名: SALM1; FIGLER2; KIAA1246

基因 ID: 57497 | 基因类型: protein coding

关于 LRFN2

Cytogenetic location: 6p21.2-p21.1 Genomic coordinates (GRCh38): 6:40,391,591-40,587,364 (from NCBI)

This gene has 2 transcripts (splice variants), 260 orthologues and 25 paralogues. Low expression observed in reference dataset.

功能概要

预计参与化学突触传递的调节和突触后组织的调节。预测位于质膜中。预测在 Schaffer 侧枝 - CA1 突触和细胞表面活跃。预计是突触后密度膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in modulation of chemical synaptic transmission and regulation of postsynapse organization. Predicted to be located in plasma membrane. Predicted to be active in Schaffer collateral - CA1 synapse and cell surface. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022]

LRFN2 基因产物(1)

mRNA Protein Name
NM_020737.3 NP_065788.1 leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor

LRFN2 蛋白结构

LRR_8

LRR_8: Leucine rich repeat (56 - 112)

LRR_8

LRR_8: Leucine rich repeat (151 - 209)

I-set

I-set: Immunoglobulin I-set domain (290 - 376)

fn3

fn3: Fibronectin type III domain (420 - 494)

  • 0
  • 200
  • 400
  • 600
  • 789 a.a.
蛋白主名 其他名称

leucine-rich repeat and fibronectin type-III domain-containing protein 2

fibronectin type III, immunoglobulin and leucine rich repeat domains 2

关联疾病

疾病名称 别名
Neuronitis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07782 LRFN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus LRFN2 VGNC VGNC:30976
Canis familiaris LRFN2 VGNC VGNC:42761
Mus musculus LRFN2 MGD MGI:1917780
Felis catus LRFN2 VGNC VGNC:63275
Macaca mulatta LRFN2 VGNC VGNC:74328
Rattus norvegicus LRFN2 RGD RGD:1311831
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