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  2. ARHGAP20 - Rho GTPase activating protein 20 Gene

ARHGAP20 - Rho GTPase activating protein 20 Gene

中文名称:Rho GTP 酶激活蛋白 20

种属: Homo sapiens

同用名: RARHOGAP

基因 ID: 57569 | 基因类型: protein coding

关于 ARHGAP20

Cytogenetic location: 11q22.3-q23.1 Genomic coordinates (GRCh38): 11:110,577,043-110,713,189 (from NCBI)

This gene has 7 transcripts (splice variants), 308 orthologues and 1 paralogue. Broad expression in fat (RPKM 5.7), testis (RPKM 5.0) and 20 other tissues.

功能概要

该基因编码的蛋白质是 RHO 型 GTP 酶的激活剂,可将信号从 RAP1 转导至 RHO 并影响神经突生长。[RefSeq 提供,2016 年 9 月]

The protein encoded by this gene is an activator of RHO-type GTPases, transducing a signal from RAP1 to RHO and impacting neurite outgrowth. [provided by RefSeq, Sep 2016]

ARHGAP20 基因产物(6)

mRNA Protein Name
NM_001258415.2 NP_001245344.1 rho GTPase-activating protein 20 isoform 2
NM_001258416.2 NP_001245345.1 rho GTPase-activating protein 20 isoform 3
NM_001258417.2 NP_001245346.1 rho GTPase-activating protein 20 isoform 4
NM_001258418.2 NP_001245347.1 rho GTPase-activating protein 20 isoform 4
NM_001384657.1 NP_001371586.1 rho GTPase-activating protein 20 isoform 1
NM_020809.4 NP_065860.2 rho GTPase-activating protein 20 isoform 1

ARHGAP20 蛋白结构

RA

RA: Ras association (RalGDS/AF-6) domain (198 - 273)

RhoGAP

RhoGAP: RhoGAP domain (377 - 523)

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  • 1191 a.a.
蛋白主名 其他名称

rho GTPase-activating protein 20

RA and RhoGAP domain containing protein

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ARHGAP20 VGNC VGNC:38050
Rattus norvegicus ARHGAP20 RGD RGD:1303160
Macaca mulatta ARHGAP20 VGNC VGNC:69862
Mus musculus ARHGAP20 MGD MGI:2445175
Bos taurus ARHGAP20 VGNC VGNC:26079
Felis catus ARHGAP20 VGNC VGNC:81903