REG1B - regenerating family member 1 beta Gene

中文名称：重生家族成员 1 测试版

种属: Homo sapiens

同用名: REGH; REGL; PSPS2; REGI-BETA

关于 REG1B

功能概要

该基因是 Reg 基因家族的 I 型亚类成员。 Reg 基因家族是一个多基因家族，根据编码蛋白质的一级结构分为四个亚类，I、II、III 和 IV 型。该基因编码一种由外分泌胰腺分泌的蛋白质，该蛋白质与 REG1A 蛋白质高度相似。相关的 REG1A 蛋白与胰岛细胞再生和糖尿病发生有关，并可能参与胰腺的结石形成。 Reg 家族成员 REG1A、REGL、PAP 和该基因串联聚集在染色体 2p12 上，可能通过基因复制产生于同一祖先基因。[RefSeq 提供，2008 年 7 月]

This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]