Prom1 - prominin 1 Gene

种属: Rattus norvegicus

同用名: Prom; CD133

关于 Prom1

功能概要

Predicted to enable actinin binding activity; cadherin binding activity; and Cholesterol binding activity. Predicted to be involved in several processes, including glomerular epithelial cell differentiation; photoreceptor cell maintenance; and retina morphogenesis in camera-type eye. Predicted to be located in several cellular components, including endoplasmic reticulum-Golgi intermediate compartment; extracellular exosome; and photoreceptor outer segment membrane. Predicted to be active in several cellular components, including apical plasma membrane; microvillus; and prominosome. Predicted to be integral component of plasma membrane. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in cone-rod dystrophy 12 and retinitis pigmentosa 41. Orthologous to human PROM1 (prominin 1). [provided by Alliance of Genome Resources, Apr 2022]