CD133/PROM1 蛋白, Rat (HEK293, His)

The CD133/PROM1 protein is critical for multiple processes including glomerular epithelial cell differentiation and retinal morphogenesis, showing biased expression in tissues such as lung and kidney. CD133/PROM1 Protein, Rat (HEK293, His) is the recombinant rat-derived CD133/PROM1 protein, expressed by HEK293 , with N-His labeled tag. The total length of CD133/PROM1 Protein, Rat (HEK293, His) is 254 a.a., with molecular weight of 47-57 KDa.

CD133/PROM1 蛋白预计具有肌动蛋白结合活性、钙粘蛋白结合活性和胆固醇结合活性。该蛋白质预计参与多种过程，包括肾小球上皮细胞分化、感光细胞维持和相机型眼睛中的视网膜形态发生。CD133 预计位于内质网-高尔基中间室、细胞外外泌体和光感受器外节膜等细胞成分中，预计在顶端质膜、微绒毛和前粒体等细胞成分中具有活性。此外，预计它是质膜的一个组成部分。CD133 用于糖尿病研究，并与锥杆营养不良 12 和色素性视网膜炎 41 等人类疾病有关。值得注意的是，CD133 在组织中表现出偏向表达，在肺、肾和其他八种组织中观察到显着水平的表达，表明其在这些器官中的不同功能作用。

Rat

HEK293

N-His

NP_001103607 (N171-Y424)

60357  [NCBI]

47-57 kDa.

Greater than 90% as determined by reducing SDS-PAGE

溶液

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.