1. Gene
  2. RNASE6 - ribonuclease A family member k6 Gene

RNASE6 - ribonuclease A family member k6 Gene

中文名称:核糖核酸酶 A 家族成员 k6

种属: Homo sapiens

同用名: RAD1; RNS6; RNasek6

基因 ID: 6039 | 基因类型: protein coding

关于 RNASE6

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:20,781,070-20,782,467 (from NCBI)

This gene has 1 transcript (splice variant), 91 orthologues and 12 paralogues. Broad expression in lymph node (RPKM 33.5), appendix (RPKM 26.6) and 24 other tissues.

功能概要

由该基因编码的蛋白质是核糖核酸酶 A 超家族的成员,在泌尿道中起作用。该蛋白对致病菌具有广谱抗菌活性。[RefSeq 提供,2014 年 11 月]

The protein encoded by this gene is a member of the ribonuclease A superfamily and functions in the urinary tract. The protein has broad-spectrum antimicrobial activity against pathogenic bacteria. [provided by RefSeq, Nov 2014]

RNASE6 基因产物(1)

mRNA Protein Name
NM_005615.5 NP_005606.1 ribonuclease K6 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA nuclease activity IDA
IDA: 通过直接分析推断
9826755 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in antibacterial humoral response IDA
IDA: 通过直接分析推断
25075772 GOA
involved in antimicrobial humoral immune response mediated by antimicrobial peptide IDA
IDA: 通过直接分析推断
25075772 GOA
involved in defense response to Gram-negative bacterium IDA
IDA: 通过直接分析推断
25075772 GOA
involved in defense response to Gram-positive bacterium IDA
IDA: 通过直接分析推断
25075772 GOA
NOT involved in defense response to virus IDA
IDA: 通过直接分析推断
9826755 GOA
involved in defense response to virus IDA
IDA: 通过直接分析推断
9826755 GOA
involved in innate immune response IDA
IDA: 通过直接分析推断
25075772 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
25075772 GOA
located in extracellular space IDA
IDA: 通过直接分析推断
25075772 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RNASE6 蛋白结构

RnaseA

RnaseA: Pancreatic ribonuclease (29 - 147)

  • 0
  • 100
  • 150 a.a.
蛋白主名 其他名称

ribonuclease K6

ribonuclease A D1

重组 RNASE6 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71261 RNASE6 Protein, Human (HEK293, His) Q93091 (W24-L150) ≥95%

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RNASE6 RGD RGD:1303020
Bos taurus RNASE6 VGNC VGNC:33999
Mus musculus RNASE6 MGD MGI:1925666
Macaca mulatta RNASE6 VGNC VGNC:76701
Others RNASE6 NCBI