RPL17 - ribosomal protein L17 Gene

中文名称：核糖体蛋白 L17

种属: Homo sapiens

同用名: L17; PD-1; RPL23

关于 RPL17

功能概要

核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 60S 亚基的一个组成部分。该蛋白属于核糖体蛋白 L22P 家族。它位于细胞质中。该基因被称为 rpL23，因为编码的蛋白质与来自海氏盐杆菌的核糖体蛋白 L23 具有相同的氨基酸；但是，它的官方符号是 RPL17。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。可变剪接导致多个转录本变体。该基因与邻近的下游 C18orf32 (染色体 18 开放阅读框 32) 基因之间也存在通读转录。[RefSeq 提供，2010 年 12 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene. [provided by RefSeq, Dec 2010]