RPL18A - ribosomal protein L18a Gene

中文名称：核糖体蛋白 L18a

种属: Homo sapiens

同用名: L18A

关于 RPL18A

功能概要

核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码核糖体蛋白 L18AE 家族的一个成员，该家族是 60S 亚基的一个组成部分。编码的蛋白质可能通过与丙型肝炎病毒内部核糖体进入位点 (IRES) 相互作用而在病毒复制中发挥作用。该基因与位于第三个内含子内的 U68 snoRNA 共同转录。对于编码核糖体蛋白的基因来说，这是典型的，该基因有多个经过处理的假基因分散在整个基因组中。[RefSeq 提供，2012 年 7 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]