2. Gene
  3. FKBPL - FKBP prolyl isomerase like Gene

FKBPL - FKBP prolyl isomerase like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：FKBP 脯氨酰异构酶样

种属: Homo sapiens

同用名: NG7; DIR1; WISP39

基因 ID: 63943 | 基因类型: protein coding

关于 FKBPL

Cytogenetic location: 6p21.32 Genomic coordinates (GRCh38): 6:32,128,707-32,130,288 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 175 orthologues and 18 paralogues. Ubiquitous expression in skin (RPKM 3.5), thyroid (RPKM 3.5) and 25 other tissues.

功能概要

由该基因编码的蛋白质与免疫亲和蛋白家族具有相似性，后者在免疫调节和涉及蛋白质折叠和运输的基本细胞过程中发挥作用。编码的蛋白质被认为在诱导的放射抗性中具有潜在作用。它似乎也参与了细胞周期的控制。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008]

FKBPL 基因产物(1)

mRNA Protein Name
NM_022110.4 NP_071393.2 FK506-binding protein-like

FKBPL 蛋白结构

TPR_11

TPR_11: TPR repeat (209 - 283)

TPR_1

TPR_1: Tetratricopeptide repeat (287 - 319)

  • 0
  • 100
  • 200
  • 300
  • 349 a.a.
蛋白主名 其他名称

FK506-binding protein-like

FK506 binding protein like

FKBPL 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra FKBPL Q9UIM3 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
25416956
Intra FKBPL Q9UIM3 CALCOCO2 Homo sapiens Q13137
Validated Y2H
25416956
Intra FKBPL Q9UIM3 ANKRD49 Homo sapiens Q8WVL7
Y2H Prey Pooling
32296183
Intra FKBPL Q9UIM3 ANKRD49 Homo sapiens Q8WVL7
Y2H Array
32296183
Intra FKBPL Q9UIM3 ANKRD49 Homo sapiens Q8WVL7
Anti Tag CoIP
25036637
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Abnormal Retinal Correspondence
Tolosa-Hunt Syndrome

Painful Ophthalmoplegia

Tolosa Hunt Syndrome

Nonspecific Inflammation Of The Cavernous Sinus Or Superior Orbital Fissure

Ths

Ophthalmoplegia, Painful
Spermatogenic Failure, Y-Linked, 2

SPGFY2

Spermatogenic Failure, Nonobstructive, Y-Linked

Y-Linked Spermatogenic Failure 2

Azoospermia, Nonobstructive, Y-Linked

Oligozoospermia, Nonobstructive, Y-Linked

Oligospermia, Nonobstructive, Y-Linked

Spermatogenic Arrest, Y-Linked

Nonobstructive Y-Linked Spermatogenic Failure

Spermatogenic Failure Y-Linked 2

Azoospermia Non-Obstructive Y-Linked

Non-Obstructive Azoospermia And Infertility

Oligospermia Non-Obstructive Y-Linked

Oligozoospermia Non-Obstructive Y-Linked

Spermatogenic Arrest Y-Linked

Spermatogenic Failure Nonobstructive Y-Linked
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04970 FKBPL Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus FKBPL MGD MGI:1932127
Bos taurus FKBPL VGNC VGNC:29028
Felis catus FKBPL VGNC VGNC:62286
Macaca mulatta FKBPL VGNC VGNC:72506
Rattus norvegicus FKBPL RGD RGD:1303227
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