RTP4 - receptor transporter protein 4 Gene

中文名称：受体转运蛋白 4

种属: Homo sapiens

同用名: IFRG28; Z3CXXC4

基因 ID: 64108 | 基因类型: protein coding

关于 RTP4

Cytogenetic location: 3q27.3 Genomic coordinates (GRCh38): 3:187,368,385-187,372,076 (from NCBI)

This gene has 1 transcript (splice variant), 86 orthologues and 4 paralogues. Ubiquitous expression in urinary bladder (RPKM 8.4), duodenum (RPKM 6.0) and 25 other tissues.

功能概要

预测可启用嗅觉受体结合活性。参与对病毒的防御反应；检测与苦味感官知觉相关的化学刺激；和蛋白质靶向膜。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable olfactory receptor binding activity. Involved in defense response to virus; detection of chemical stimulus involved in sensory perception of bitter taste; and protein targeting to membrane. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RTP4 基因产物(1)

mRNA	Protein	Name
NM_022147.3	NP_071430.2	receptor-transporting protein 4

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	16720576	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in defense response to virus	IDA IDA: 通过直接分析推断	21478870	GOA
involved in detection of chemical stimulus involved in sensory perception of bitter taste	IDA IDA: 通过直接分析推断	16720576	GOA
involved in protein targeting to membrane	IDA IDA: 通过直接分析推断	16720576	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	16720576	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RTP4 蛋白结构

zf-3CxxC

0
100
200
246 a.a.

蛋白主名

其他名称

receptor-transporting protein 4

28 kDa interferon-responsive protein

RTP4 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	RTP4	Q96DX8	DERL3	Homo sapiens	Q96Q80	Validated Y2H	32296183
Intra	RTP4	Q96DX8	TAS2R10	Homo sapiens	Q9NYW0	Validated Y2H	32296183
Intra	RTP4	Q96DX8	REEP4	Homo sapiens	Q9H6H4	Y2H Prey Pooling	32296183
Intra	RTP4	Q96DX8	REEP4	Homo sapiens	Q9H6H4	Validated Y2H	32296183
Intra	RTP4	Q96DX8	REEP4	Homo sapiens	Q9H6H4	Y2H Array	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Malaria

Malaria, Susceptibility To	Malaria, Resistance To
Malaria, Cerebral	Cerebral Malaria
Malaria, Severe, Susceptibility To	Malaria, Severe, Resistance To
Malaria, Cerebral, Susceptibility To	Induced Malaria
Malaria, Vivax, Protection Against	Malaria, Severe
Malaria, Cerebral, Reduced Risk Of	Malaria, Protection Against
Resistance To Malaria Due To G6pd Deficiency	Malaria Due To G6pd Deficiency
Malarial Encephalitis	CM
Malaria Cerebral	Susceptibility To Malaria
Acute Pernicious Fever	Aestivo-Autumnal Fever
Aestivo Autumnal Malaria	Chagres Fever
Continued Malaria Fever	Estivo-Autumnal Fever
Estivo-Autumnal Malaria	Estivo-Autumnal Malarial Fever
Falciparum Fever	Malignant Tertian Fever
Malignant Tertian Malaria	Pernicious Intermittent Fever
Pernicious Malaria	Quotidian Malaria
Subtertian Fever	Subtertian Malaria Fever
Subtertian Malignant Tertian Malaria	Tropical Malaria
Algid Malaria	Bilious Haemoglobinuric Fever
Black Water Fever	Blackwater Fever
Malarial Blackwater Fever	Severe Malarial Falciparum
West African Fever	Malarial Haematinuria
Haemoglobinuric Fever	Haemoglobinuric Malaria
Severe Plasmodium Falciparum Malaria	Malarial Haemoglobinuria
Malarial Haematuria	Falciparum Malaria [Malignant Tertian]
Malaria Tropica	Malarial Shock
Chagres Virus Disease	Malignant Malaria
Mtm - [Malignant Tertian Malaria]	Tm -[Malignant Tertian Malaria]
Panama Fever	St - [Subtertian Malaria]
Malarial Quotidian	Benign Tertian Malaria
Tertian Ague	Vivax Fever
Plasmodium Vivax Malaria Nos	Btm - [Benign Tertian Malaria]
Bt - [Benign Tertian Malaria]	Vivax Malaria
Benign Tertian Vivax Malaria	Tertian Malaria
Quartan Malaria	Quartan Ague
Quartan Fever	Plasmodium Malariae Malaria Nos
Quartan Malarial	Malaria By Plasmodium Malariae
Malariae Malaria	Ovale Tertian Malaria
Plasmodium Ovale Fever	Malaria Fever By Plasmodium Ovale
Ovale Malaria	Malaria By Plasmodium Ovale
Malarial Ovale	Marsh Fever
Remittent Congestive Fever	Coastal Fever
Remittent Gastric Fever	Miasmatic Fever
Congestive Remittent Fever	Intermittent Fever
Jungle Fever	Paludism
Cameroon Fever	Ague
Corsican Fever	Intermittent Bilious Fever
Disease Due To Plasmodiidae	Malarial Fever
Plasmodiosis	Remittent Fever
Roman Fever	Malaria Fever Nos
Malaria Nos	Paludal Fever
Clinically Diagnosed Malaria	Clinically Diagnosed Malaria Without Parasitological Confirmation
Congestive Fever	Malarial Cachexia
Marsh Cachexia	Paludal Cachexia
Recurrent Malaria	Remittent Malaria

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12339	RTP4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	RTP4	RGD	RGD:1306974
Macaca mulatta	RTP4	VGNC	VGNC:77090
Canis familiaris	RTP4	VGNC	VGNC:53463
Mus musculus	RTP4	MGD	MGI:1915025
Felis catus	RTP4	VGNC	VGNC:102835
Bos taurus	RTP4	VGNC	VGNC:53603

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