1. Gene
  2. TAS2R10 - taste 2 receptor member 10 Gene

TAS2R10 - taste 2 receptor member 10 Gene

中文名称:味觉 2 受体成员 10

种属: Homo sapiens

同用名: TRB2; T2R10

基因 ID: 50839 | 基因类型: protein coding

关于 TAS2R10

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,825,219-10,826,358 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 199 orthologues and 23 paralogues.

功能概要

该基因产物属于候选味觉受体家族,是 G 蛋白偶联受体超家族的成员。这些蛋白质在舌头和上颚上皮细胞的味觉受体细胞中特异性表达。它们以簇的形式组织在基因组中,并与影响小鼠和人类苦味感知的基因座有遗传联系。在功能表达研究中,它们对促苦味剂有反应。该基因映射到染色体 12p13 上的味觉受体基因簇。[RefSeq 提供,2008 年 7 月]

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the Taste Receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the Taste Receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]

TAS2R10 基因产物(1)

mRNA Protein Name
NM_023921.2 NP_076410.1 taste receptor type 2 member 10
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables bitter taste receptor activity IDA
IDA: 通过直接分析推断
20022913 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in detection of chemical stimulus involved in sensory perception of bitter taste IDA
IDA: 通过直接分析推断
20022913 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

TAS2R10 蛋白结构

TAS2R

TAS2R: Taste receptor protein (TAS2R) (1 - 296)

  • 0
  • 100
  • 200
  • 307 a.a.
蛋白主名 其他名称

taste receptor type 2 member 10

taste receptor, family B, member 2

TAS2R10 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TAS2R10 Q9NYW0 RTP4 Homo sapiens Q96DX8
Y2H Prey Pooling
32296183
Intra TAS2R10 Q9NYW0 RTP4 Homo sapiens Q96DX8
Y2H Array
32296183
Intra TAS2R10 Q9NYW0 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Array
32296183
Intra TAS2R10 Q9NYW0 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Prey Pooling
32296183
Intra TAS2R10 Q9NYW0 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra TAS2R10 Q9NYW0 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra TAS2R10 Q9NYW0 HERPUD2 Homo sapiens Q9BSE4
Y2H Array
32296183
Intra TAS2R10 Q9NYW0 HERPUD2 Homo sapiens Q9BSE4
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TAS2R10 RGD RGD:2314260
Canis familiaris TAS2R10 VGNC VGNC:47115