1. Gene
  2. LINGO3 - leucine rich repeat and Ig domain containing 3 Gene

LINGO3 - leucine rich repeat and Ig domain containing 3 Gene

中文名称:含富亮氨酸的重复序列和 Ig 结构域 3

种属: Homo sapiens

同用名: LERN2; LRRN6B

基因 ID: 645191 | 基因类型: protein coding

关于 LINGO3

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:2,287,164-2,308,154 (from NCBI)

This gene has 2 transcripts (splice variants), 373 orthologues and 10 paralogues. Biased expression in spleen (RPKM 1.7), brain (RPKM 0.7) and 7 other tissues.

功能概要

预计是膜的组成部分。预计在细胞外基质和细胞外空间中具有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be integral component of membrane. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

LINGO3 基因产物(1)

mRNA Protein Name
NM_001101391.3 NP_001094861.1 leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 precursor

LINGO3 蛋白结构

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (24 - 53)

LRR_8

LRR_8: Leucine rich repeat (58 - 114)

LRR_8

LRR_8: Leucine rich repeat (151 - 207)

LRR_8

LRR_8: Leucine rich repeat (247 - 303)

I-set

I-set: Immunoglobulin I-set domain (412 - 497)

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  • 592 a.a.
蛋白主名 其他名称

leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3

leucine rich repeat neuronal 6B

关联疾病

疾病名称 别名
Retinitis Pigmentosa 19

RP19

Retinitis Pigmentosa-19

Retinitis Pigmentosa, Type 19

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LINGO3 RGD RGD:1592209
Canis familiaris LINGO3 VGNC VGNC:42690
Bos taurus LINGO3 VGNC VGNC:30901
Mus musculus LINGO3 MGD MGI:3609246