2. Gene
  3. IL25 - interleukin 25 Gene

IL25 - interleukin 25 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：白细胞介素 25

种属: Homo sapiens

同用名: IL17E

基因 ID: 64806 | 基因类型: protein coding

关于 IL25

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:23,372,809-23,376,403 (from NCBI)

This gene has 2 transcripts (splice variants), 89 orthologues and 5 paralogues. Low expression observed in reference dataset.

功能概要

该基因编码的蛋白质是一种与白细胞介素 17 具有序列相似性的细胞因子。这种细胞因子可以诱导 NF-kappaB 激活，并刺激白细胞介素 8 的产生。这种细胞因子和白细胞介素 17B 都是细胞因子受体 IL17BR 的配体。对小鼠相似基因的研究表明，这种细胞因子可能是一种有利于 Th2 型免疫反应的促炎细胞因子。可变剪接导致多个转录本变体。[RefSeq 提供，2010 年 3 月]

The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

IL25 基因产物(2)

mRNA Protein Name
NM_022789.4 NP_073626.1 interleukin-25 isoform 1 precursor
NM_172314.2 NP_758525.1 interleukin-25 isoform 2 precursor

IL25 蛋白结构

IL17

IL17: Interleukin-17 (85 - 172)

  • 0
  • 100
  • 177 a.a.
蛋白主名 其他名称

interleukin-25

interleukin-17E

重组 IL25 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72555 IL-25/IL-17E Protein, Human (HEK293, His) Q9H293-1 (Y33-G177) ≥95%
HY-P74813 IL-25/IL-17E Protein, Human (HEK293, Fc) Q9H293-1 (Y33-G177) ≥95%
HY-P700116AF Animal-Free IL-25/IL-17E Protein, Human (His) Q9H293-1 (Y33-G177) ≥95%
HY-P701012 IL-25/IL-17E Protein, Human (Biotinylated, HEK293, His-Avi) Q9H293-1 (Y33-G177) ≥95%

关联疾病

疾病名称 别名
Chronic Mucocutaneous Candidiasis

Candidiasis, Chronic Mucocutaneous

Cmc

Candidiasis Chronic Mucocutaneous
Psoriasis 11

PSORS11

Psoriasis Susceptibility 11

Psoriasis

Psoriasis Vulgaris

Psoriasis 11, Susceptibility To

Pv
Nail Disease

Nail Diseases

Abnormality Of The Nail

Nail Anomaly
Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06744 IL25 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus IL25 MGD MGI:2155888
Canis familiaris IL25 VGNC VGNC:41975
Bos taurus IL25 VGNC VGNC:30149
Felis catus IL25 VGNC VGNC:80950
Macaca mulatta IL25 VGNC VGNC:84356
Rattus norvegicus IL25 RGD RGD:1561632
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