1. Gene
  2. FNDC4 - fibronectin type III domain containing 4 Gene

FNDC4 - fibronectin type III domain containing 4 Gene

中文名称:含纤连蛋白 III 型域 4

种属: Homo sapiens

同用名: FRCP1

基因 ID: 64838 | 基因类型: protein coding

关于 FNDC4

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,491,883-27,495,200 (from NCBI)

This gene has 3 transcripts (splice variants), 152 orthologues and 1 paralogue. Biased expression in adrenal (RPKM 35.7), brain (RPKM 13.1) and 11 other tissues.

功能概要

参与对转化生长因子 β 的反应。预测位于内质网和细胞外间隙。预计在细胞外区域和质膜中具有活性。 [由基因组资源联盟提供,2022 年 4 月]

Involved in response to transforming growth factor beta. Predicted to be located in endoplasmic reticulum and extracellular space. Predicted to be active in extracellular region and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

FNDC4 基因产物(1)

mRNA Protein Name
NM_022823.3 NP_073734.1 fibronectin type III domain-containing protein 4 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to transforming growth factor beta IEP
IEP: 通过表达模式推断
27066907 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

FNDC4 蛋白结构

fn3

fn3: Fibronectin type III domain (48 - 129)

  • 0
  • 100
  • 200
  • 234 a.a.
蛋白主名 其他名称

fibronectin type III domain-containing protein 4

fibronectin type III repeat-containing protein 1

重组 FNDC4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76935 FNDC4 Protein, Human (HEK293, Fc) Q9H6D8/NP_073734.1 (D45-T167) ≥95%

关联疾病

疾病名称 别名
Colitis
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta FNDC4 VGNC VGNC:72538
Felis catus FNDC4 VGNC VGNC:62321
Rattus norvegicus FNDC4 RGD RGD:6496095
Bos taurus FNDC4 VGNC VGNC:29064
Canis familiaris FNDC4 VGNC VGNC:40930
Mus musculus FNDC4 MGD MGI:1917195
Others FNDC4 NCBI