1. Gene
  2. ANXA8 - annexin A8 Gene

ANXA8 - annexin A8 Gene

中文名称:膜联蛋白 A8

种属: Homo sapiens

同用名: ANX8; CH17-360D5.2

基因 ID: 653145 | 基因类型: protein coding

关于 ANXA8

Cytogenetic location: 10q11.22 Genomic coordinates (GRCh38): 10:47,467,993-47,991,796 (from NCBI)

This gene has 8 transcripts (splice variants), 336 orthologues and 12 paralogues. Biased expression in skin (RPKM 96.8), esophagus (RPKM 57.8) and 3 other tissues.

功能概要

该基因编码进化上保守的 Ca2+ 和磷脂结合蛋白的膜联蛋白家族的成员。所编码的蛋白质可用作间接抑制促凝血酶原激酶特异性复合物的抗凝血剂。该基因的过度表达与急性髓细胞白血病有关。在 10 号染色体的长臂附近发现了该基因的高度相似的复制副本。[RefSeq 提供,2008 年 7 月]

This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008]

ANXA8 基因产物(3)

mRNA Protein Name
NM_001040084.3 NP_001035173.1 annexin A8 isoform 2
NM_001271702.2 NP_001258631.1 annexin A8 isoform 1
NM_001271703.2 NP_001258632.1 annexin A8 isoform 3

ANXA8 蛋白结构

Annexin

Annexin: Annexin (26 - 90)

Annexin

Annexin: Annexin (97 - 162)

Annexin

Annexin: Annexin (181 - 246)

Annexin

Annexin: Annexin (257 - 322)

  • 0
  • 100
  • 200
  • 300
  • 327 a.a.
蛋白主名 其他名称

annexin A8

VAC-beta

重组 ANXA8 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7520 Annexin A8/ANXA8 Protein, Human P13928 (M1-P327) ≥95%
HY-P75505 Annexin A8/ANXA8 Protein, Human (His) P13928-1 (M1-P327) ≥95%

关联疾病

疾病名称 别名
Breast Adenocarcinoma

Mammary Adenocarcinoma

Adenocarcinoma Of Breast

Metagonimiasis

Trematode Infections

Infection By Metagonimus Yokogawai

Metagonimus Yokogawai Infection

Heterophyiasis

Heterophyes Infectious Disease

Acute Laryngopharyngitis

Pharyngolaryngitis

Laryngopharyngitis

Hypopharyngitis

Trachea Leiomyoma

Tracheal Neoplasms

Leiomyoma Of The Trachea

Tracheal Neoplasm

Tracheal Leiomyoma

Aortic Aneurysm, Familial Abdominal, 1

Abdominal Aortic Aneurysm

Aortic Aneurysm, Familial Abdominal 1

Aneurysm, Abdominal Aortic

AAA

Aortic Aneurysm, Abdominal

AAA1

Aortic Aneurysm, Familial Abdominal

Aortic Aneurysm Abdominal

Abdominal Aortic Aneurysms

Abdominal Aortic Aneurysm Without Mention Of Perforation Or Rupture

Abdomen Aneurysm

Abdominal Aorta Aneurysm

Aneurysm Of Abdominal Aorta

Aortic Abdomen Aneurysm

Aaa - [Abdominal Aortic Aneurysm]

Abdominal Aneurysm

Abdominal Aorta Aneurysm Rupture

Abdominal Aorta Aneurysm Ruptured

Abdominal Aortic Aneurysm Which Has Ruptured

Ruptured Aaa

Abdomen Aorta Aneurysm Ruptured

Abdomen Aorta Rupture

Abdomen Aortic Aneurysm Rupture

Abdomen Aneurysm Rupture

Abdomen Aortic Aneurysm Ruptured

Abdomen Aortic Rupture

Abdominal Aorta Rupture

Abdominal Aortic Rupture

Rupture Abdomen Aorta Aneurysm

Rupture Abdominal Aortic Aneurysm

Ruptured Abdomen Aneurysm

Ruptured Abdomen Aorta

Ruptured Abdomen Aortic

Ruptured Abdominal Aneurysm

Ruptured Abdominal Aorta

Ruptured Abdominal Aortic

Ruptured Aorta Abdominalis Aneurysm

False Abdomen Aorta Aneurysm Ruptured

False Abdominal Aortic Aneurysm Ruptured

False Abdominal Aorta Aneurysm Ruptured

False Abdomen Aortic Aneurysm Ruptured

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus ANXA8 MGD MGI:1201374
Rattus norvegicus ANXA8 RGD RGD:1307719