Annexin A8/ANXA8 蛋白, Human (His)

The annexin A8 (ANXA8) protein acts as an anticoagulant, indirectly inhibiting the thromboplastin-specific complex in the coagulation cascade. Its regulatory role underscores its importance in regulating key components of the coagulation pathway, highlighting its potential to influence the delicate balance between pro- and anticoagulant factors. Annexin A8/ANXA8 Protein, Human (His) is the recombinant human-derived Annexin A8/ANXA8 protein, expressed by E. coli , with N-6*His labeled tag.

膜联蛋白 A8 (ANXA8) 蛋白作为抗凝剂，在凝血级联中作为凝血活酶特异性复合物的间接抑制剂。它在调节凝血活酶特异性复合物中的调节作用强调了它在影响凝血途径的关键组成部分方面的重要性，表明它对血液凝固过程中促凝血因子和抗凝血因子之间的微妙平衡的潜在贡献。ANXA8 干预凝血活酶相关相互作用的能力强调了其作为控制血液凝固的复杂调节机制网络中调节剂的重要性，揭示了其在治疗凝血障碍方面的潜在治疗意义。

Human

E. coli

N-6*His

P13928-1 (M1-P327)

653145  [NCBI]

MAWWKSWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSDP

Approximately 38 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from sterile 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.