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  3. SLC15A1 - solute carrier family 15 member 1 Gene

SLC15A1 - solute carrier family 15 member 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 15 成员 1

种属: Homo sapiens

同用名: PEPT1; HPECT1; HPEPT1

基因 ID: 6564 | 基因类型: protein coding

关于 SLC15A1

Cytogenetic location: 13q32.2-q32.3 Genomic coordinates (GRCh38): 13:98,683,801-98,752,672 (from NCBI)

This gene has 2 transcripts (splice variants), 264 orthologues and 4 paralogues. Biased expression in small intestine (RPKM 105.5), duodenum (RPKM 76.1) and 2 other tissues.

功能概要

该基因编码一种肠氢肽协同转运蛋白，它是溶质载体家族 15 的一员。编码的蛋白质定位于肠上皮细胞的刷状缘膜，并介导二肽和三肽从肠腔摄取到肠细胞中。这种蛋白质在膳食蛋白质的摄取和消化中起着重要作用。这种蛋白质还有助于许多拟肽药物的吸收。[RefSeq 提供，2010 年 4 月]

This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and Tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. [provided by RefSeq, Apr 2010]

SLC15A1 基因产物(1)

mRNA Protein Name
NM_005073.4 NP_005064.1 solute carrier family 15 member 1

SLC15A1 蛋白结构

PTR2

PTR2: POT family (81 - 474)

  • 0
  • 200
  • 400
  • 600
  • 708 a.a.
蛋白主名 其他名称

solute carrier family 15 member 1

Caco-2 oligopeptide transporter

关联疾病

疾病名称 别名
Short Bowel Syndrome

Short Gut Syndrome

Acquired Short Bowel Syndrome

Secondary Short Bowel Syndrome

Short Bowel Nos
Hartnup Disorder

Hartnup Disease

HND

Neutral 1 Amino Acid Transport Defect

Neutral Amino Acid Transport Defect

Deficiency Of Tryptophan Oxygenase

Hartnup'S Disease

Aminoaciduria, Hartnup Type

Disorder Of Neutral Amino Acid Transport
Meckel Diverticulum

Meckel'S Diverticulum

Persistent Vitelline Duct
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory
Iminoglycinuria

Iminoglycinuria, Digenic

IG
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13012 SLC15A1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SLC15A1 VGNC VGNC:46232
Mus musculus SLC15A1 MGD MGI:1861376
Macaca mulatta SLC15A1 VGNC VGNC:77393
Bos taurus SLC15A1 VGNC VGNC:34679
Rattus norvegicus SLC15A1 RGD RGD:621736
Felis catus SLC15A1 VGNC VGNC:65200
Others SLC15A1 NCBI
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