2. Gene
  3. Piezo2 - piezo-type mechanosensitive ion channel component 2 Gene

Piezo2 - piezo-type mechanosensitive ion channel component 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fam38b; Fam38b2; 5930434P17; 9030411M15Rik; 9430028L06Rik

基因 ID: 667742 | 基因类型: protein coding

关于 Piezo2

功能概要

Enables mechanosensitive cation channel activity. Involved in detection of mechanical stimulus involved in sensory perception. Acts upstream of or within cation transport and regulation of membrane potential. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in dorsal root ganglion and lung. Human ortholog(s) of this gene implicated in distal arthrogryposis type 3 and distal arthrogryposis type 5. Orthologous to human PIEZO2 (piezo type mechanosensitive ion channel component 2). [provided by Alliance of Genome Resources, Apr 2022]

Piezo2 基因产物(1)

mRNA Protein Name
NM_001039485.4 NP_001034574.4 piezo-type mechanosensitive ion channel component 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mechanosensitive monoatomic ion channel activity IDA
IDA: 通过直接分析推断
20813920 MGI
enables monoatomic cation channel activity IDA
IDA: 通过直接分析推断
20813920 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24662763 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in detection of mechanical stimulus involved in sensory perception IMP
IMP: 通过突变表型推断
24717433 MGI
involved in monoatomic cation transport IMP
IMP: 通过突变表型推断
20813920 MGI
acts upstream of or within regulation of membrane potential IDA
IDA: 通过直接分析推断
20813920 MGI
involved in response to mechanical stimulus IDA
IDA: 通过直接分析推断
38568807 MGI
involved in response to mechanical stimulus IMP
IMP: 通过突变表型推断
24717433 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cuticular plate IDA
IDA: 通过直接分析推断
38228630 MGI
located in neuronal cell body membrane IDA
IDA: 通过直接分析推断
38568807 MGI
located in stereocilium IDA
IDA: 通过直接分析推断
38228630 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

piezo-type mechanosensitive ion channel component 2

family with sequence similarity 38, member B

family with sequence similarity 38, member B2

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1410C D-GsMTx4 TFA Inhibitor 99.89% 否
HY-131018 Jedi2 99.93% 否
HY-P1410B D-GsMTx4 Inhibitor 99.59% 否
HY-RS16250 Piezo2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10484 PIEZO2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Piezo2 NCBI NCBI:63895
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