1. Gene
  2. Cntnap2 - contactin associated protein-like 2 Gene

Cntnap2 - contactin associated protein-like 2 Gene

种属: Mus musculus

同用名: Caspr2; mKIAA0868; 5430425M22Rik

基因 ID: 66797 | 基因类型: protein coding

关于 Cntnap2

功能概要

Enables PDZ domain binding activity. Involved in several processes, including chemical synaptic transmission; nervous system development; and synapse organization. Acts upstream of or within glutamatergic neuron differentiation; limbic system development; and neuron projection development. Located in several cellular components, including cerebellar granule cell to Purkinje cell synapse; main axon; and presynaptic active zone membrane. Is integral component of membrane. Part of voltage-gated Potassium Channel complex. Is active in dendrite and excitatory synapse. Is expressed in central nervous system and neural retina. Used to study autism spectrum disorder and cortical dysplasia-focal epilepsy syndrome. Human ortholog(s) of this gene implicated in several diseases, including Pitt-Hopkins syndrome; autism spectrum disorder (multiple); communication disorder (multiple); cortical dysplasia-focal epilepsy syndrome; and social phobia. Orthologous to human CNTNAP2 (contactin associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Cntnap2 基因产物(2)

mRNA Protein Name
NM_001004357.2 NP_001004357.2 contactin-associated protein-like 2 isoform a precursor
NM_025771.3 NP_080047.1 contactin-associated protein-like 2 isoform b
蛋白主名 其他名称

contactin-associated protein-like 2

cell recognition molecule Caspr2

重组 Cntnap2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75604 CASPR2 Protein, Mouse (HEK293, His) NP_001004357.2 (A28-S1262) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cntnap2 NCBI NCBI:26047