2. Gene
  3. SSR3 - signal sequence receptor subunit 3 Gene

SSR3 - signal sequence receptor subunit 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：信号序列受体亚基 3

种属: Homo sapiens

同用名: TRAPG

基因 ID: 6747 | 基因类型: protein coding

关于 SSR3

Cytogenetic location: 3q25.31 Genomic coordinates (GRCh38): 3:156,539,553-156,555,117 (from NCBI)

This gene has 9 transcripts (splice variants) and 223 orthologues. Ubiquitous expression in thyroid (RPKM 48.0), endometrium (RPKM 38.4) and 25 other tissues.

功能概要

信号序列受体 (SSR) 是一种糖基化内质网 (ER) 膜受体，与跨 ER 膜的蛋白质易位相关。 SSR 由四种膜蛋白/亚基组成：α、β、γ 和 δ。前两个是糖基化亚基，后两个是非糖基化亚基。该基因编码 γ 亚基，预计它会跨膜四次。[RefSeq 提供，2010 年 8 月]

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins/subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non-glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times. [provided by RefSeq, Aug 2010]

SSR3 基因产物(4)

mRNA Protein Name
NM_001308197.2 NP_001295126.1 translocon-associated protein subunit gamma isoform 1
NM_001308204.2 NP_001295133.1 translocon-associated protein subunit gamma isoform 3
NM_001308205.2 NP_001295134.1 translocon-associated protein subunit gamma isoform 3
NM_007107.5 NP_009038.1 translocon-associated protein subunit gamma isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SSR3 蛋白结构

TRAP-gamma

TRAP-gamma: Translocon-associated protein, gamma subunit (TRAP-gamma) (12 - 183)

  • 0
  • 100
  • 185 a.a.
蛋白主名 其他名称

translocon-associated protein subunit gamma

SSR gamma

关联疾病

疾病名称 别名
Congenital Disorder Of Glycosylation, Type In

Congenital Disorder Of Glycosylation

CDG1N

Congenital Disorders Of Glycosylation

Cdg In

Cdgin

Congenital Disorder Of Glycosylation 1n

Carbohydrate-Deficient Glycoprotein Syndrome

Cdg

Rft1-Cdg

Cdg-In

Congenital Disorder Of Glycosylation Type In

Carbohydrate Deficient Glycoprotein Syndrome

Cdg Syndrome

Congenital Disorder Of Glycosylation In

Carbohydrate-Deficient Glycoprotein Syndromes

Cdg Syndrome Type In

Carbohydrate Deficient Glycoprotein Syndrome Type In

Congenital Disorder Of Glycosylation Type 1n

Man5glcnac2-Pp-Dol Flippase Deficiency

Glycosylation, Congenital Disorder Of

Glycosylation, Congenital Disorder Of, Type In
Tylosis With Esophageal Cancer

Palmoplantar Keratoderma-Esophageal Carcinoma Syndrome

TOC

Keratosis Palmaris Et Plantaris With Esophageal Cancer

Bennion-Patterson Syndrome

Howell-Evans Syndrome

Keratosis Palmoplantaris-Esophageal Carcinoma Syndrome

Palmoplantar Hyperkeratosis-Esophageal Carcinoma Syndrome

Tylosis-Oesophageal Carcinoma Syndrome

Palmoplantar Keratoderma With Esophageal Cancer

Howel-Evans Syndrome

Keratosis Palmoplantaris With Esophageal Cancer

Tylosis - Oesophageal Carcinoma

Howel-Evans' Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13816 SSR3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SSR3 VGNC VGNC:46839
Felis catus SSR3 VGNC VGNC:97645
Bos taurus SSR3 VGNC VGNC:35321
Mus musculus SSR3 MGD MGI:1914687
Rattus norvegicus SSR3 RGD RGD:621630
Macaca mulatta SSR3 VGNC VGNC:82769
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