1. Gene
  2. BRS3 - bombesin receptor subtype 3 Gene

BRS3 - bombesin receptor subtype 3 Gene

中文名称:铃蟾肽受体亚型 3

种属: Homo sapiens

同用名: BB3; BB3R; BBR3

基因 ID: 680 | 基因类型: protein coding

关于 BRS3

Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:136,487,947-136,493,780 (from NCBI)

This gene has 1 transcript (splice variant), 125 orthologues and 15 paralogues. Low expression observed in reference dataset.

功能概要

该基因编码的蛋白质是一种 G 蛋白偶联膜受体,可结合铃蟾肽样肽。这种结合导致磷脂酰肌醇-钙第二信使系统的激活,具有生理效应,包括调节代谢率、葡萄糖代谢和高血压。[RefSeq 提供,2011 年 9 月]

The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like Peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011]

BRS3 基因产物(1)

mRNA Protein Name
NM_001727.2 NP_001718.1 bombesin receptor subtype-3

BRS3 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (64 - 328)

  • 0
  • 100
  • 200
  • 300
  • 399 a.a.
蛋白主名 其他名称

bombesin receptor subtype-3

BRS-3

G-protein coupled receptor

bombesin like receptor 3

关联疾病

疾病名称 别名
Jejunal Somatostatinoma

Jejunal Delta Cell Somatostatin Producing Tumor

Somatosatinoma Of Jejunum

Jejunal Somatostatin-Producing Neuroendocrine Tumor

Brugada Syndrome 4

BRGDA4

Brugada Syndrome, Type 4

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Protection Against

Lung Cancer, Susceptibility To

Adenocarcinoma Of Lung, Somatic

Nonsmall Cell Lung Cancer

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Brugada Syndrome

Sudden Unexpected Nocturnal Death Syndrome

Sudden Unexplained Nocturnal Death Syndrome

Bangungut

Brugada Type Idiopathic Ventricular Fibrillation

Pokkuri Death Syndrome

Sunds

Idiopathic Ventricular Fibrillation, Brugada Type

Sudden Unexplained Death

Dream Disease

Right Bundle Branch Block, St Segment Elevation, And Sudden Death Syndrome

Sudden Unexplained Death Syndrome

Suds

Sunds - [Sudden Unexplained Nocturnal Death Syndrome]

Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Obesity , Susceptibility To

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis

Fetal Hemoglobin Quantitative Trait Locus 1

Hereditary Persistence Of Fetal Hemoglobin

Delta-Beta-Thalassemia

Delta-Beta Thalassemia

Delta Beta-Thalassemia

HBFQTL1

Hemoglobin F, Hereditary Persistence Of

Hpfh

Hereditary Persistence Of Fetal Hemoglobin, Hb Gene Cluster-Related

Hemoglobin, Fetal, Quantitative Trait Locus 1

Hereditary Persistence Of Fetal Hemoglobin Thalassemia

Hpfh - [Hereditary Persistence Of Fetal Haemoglobin]

Fetal Haemoglobin

Persistence Of Fetal Haemoglobin

Persistent Haemoglobin F

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus BRS3 VGNC VGNC:60183
Canis familiaris BRS3 VGNC VGNC:38535
Mus musculus BRS3 MGD MGI:1100501
Rattus norvegicus BRS3 RGD RGD:628645
Bos taurus BRS3 VGNC VGNC:26574