1. Gene
  2. Ifnar2 - interferon alpha and beta receptor subunit 2 Gene

Ifnar2 - interferon alpha and beta receptor subunit 2 Gene

中文名称:干扰素 α 和 β 受体亚基 2

种属: Rattus norvegicus

基因 ID: 686326 | 基因类型: protein coding

关于 Ifnar2

Primary_assembly 11: 30,613,767-30,668,124 forward strand.mRatBN7.2:CM026984.1

This gene has 1 transcript (splice variant), 303 orthologues, 11 paralogues and is associated with 9 phenotypes. Biased expression in Lung (RPKM 163.2), Liver (RPKM 149.8) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动蛋白激酶结合活性; I 型干扰素结合活性;和 I 型干扰素受体活性。预计参与对其他生物体的防御反应;对干扰素-α 的反应;以及对干扰素-β 的反应。预测作用于细胞群增殖的上游或内部,以及 RNA 聚合酶 II 的转录调节。预计位于细胞外空间。预计是质膜的组成部分。该基因与乙型肝炎和免疫缺陷 45 相关的人类直向同源基因。与人类 IFNAR2(干扰素 α 和 β 受体亚基 2)直向同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable protein kinase binding activity; type I interferon binding activity; and type I interferon receptor activity. Predicted to be involved in defense response to Other organism; response to interferon-alpha; and response to interferon-beta. Predicted to act upstream of or within cell population proliferation and regulation of transcription by RNA polymerase II. Predicted to be located in extracellular space. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in hepatitis B and immunodeficiency 45. Orthologous to human IFNAR2 (interferon alpha and beta receptor subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Ifnar2 基因产物(3)

mRNA Protein Name
XM_039088780.1 XP_038944708.1 interferon alpha/beta receptor 2 isoform X2
XM_006248107.4 XP_006248169.1 interferon alpha/beta receptor 2 isoform X1
XM_039088781.1 XP_038944709.1 interferon alpha/beta receptor 2 isoform X3

Ifnar2 蛋白结构

FN3

FN3: cl21522 (12 - 106)

FN3

FN3: cl21522 (132 - 229)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 516 a.a.
蛋白主名 其他名称

interferon alpha/beta receptor 2

interferon (alpha, beta and omega) receptor 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ifnar2 NCBI NCBI:3455
Macaca fascicularis Ifnar2 NCBI NCBI:102140083
Mus musculus Ifnar2 NCBI NCBI:15976