1. Gene
  2. Lpar6 - lysophosphatidic acid receptor 6 Gene

Lpar6 - lysophosphatidic acid receptor 6 Gene

中文名称:溶血磷脂酸受体 6

种属: Rattus norvegicus

同用名: P2ry5

基因 ID: 691774 | 基因类型: protein coding

关于 Lpar6

Primary_assembly 15: 48,416,544-48,422,331 forward strand.mRatBN7.2:CM026988.1

This gene has 1 transcript (splice variant), 244 orthologues, 14 paralogues and is associated with 8 phenotypes.

功能概要

预测该基因编码的蛋白编码的蛋白可启动溶血磷脂酸受体活性。预计参与磷脂酶 C 激活 G 蛋白偶联信号通路中 Rho 蛋白信号转导的正向调节和胞质钙离子浓度的正向调节。预计在胚泡孵化的上游或内部发挥作用。预测位于质膜中。预计是质膜的组成部分。该基因的人类直系同源物与少毛症有关。与人类 LPAR6(溶血磷脂酸受体 6)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable lysophosphatidic acid receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway. Predicted to act upstream of or within blastocyst hatching. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in hypotrichosis. Orthologous to human LPAR6 (lysophosphatidic acid receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Lpar6 基因产物(1)

mRNA Protein Name
NM_001045843.1 NP_001039308.1 lysophosphatidic acid receptor 6

Lpar6 蛋白结构

7tmA_LPAR6_P2Y5

7tmA_LPAR6_P2Y5: cd15156 (17 - 44)

7tmA_LPAR6_P2Y5

7tmA_LPAR6_P2Y5: cd15156 (17 - 301)

7tmA_LPAR6_P2Y5

7tmA_LPAR6_P2Y5: cd15156 (51 - 76)

7tmA_LPAR6_P2Y5

7tmA_LPAR6_P2Y5: cd15156 (88 - 118)

7tmA_LPAR6_P2Y5

7tmA_LPAR6_P2Y5: cd15156 (130 - 152)

7tmA_LPAR6_P2Y5

7tmA_LPAR6_P2Y5: cd15156 (180 - 209)

7tmA_LPAR6_P2Y5

7tmA_LPAR6_P2Y5: cd15156 (221 - 251)

7tmA_LPAR6_P2Y5

7tmA_LPAR6_P2Y5: cd15156 (269 - 294)

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  • 344 a.a.
蛋白主名 其他名称

lysophosphatidic acid receptor 6

LPA receptor 6

LPA-6

P2Y purinoceptor 5

P2Y5

oleoyl-L-alpha-lysophosphatidic acid receptor

purinergic receptor 5

purinergic receptor P2Y, G-protein coupled, 5

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lpar6 NCBI NCBI:10161