2. Gene
  3. TCF15 - transcription factor 15 Gene

TCF15 - transcription factor 15 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：转录因子 15

种属: Homo sapiens

同用名: EC2; PARAXIS; bHLHa40

基因 ID: 6939 | 基因类型: protein coding

关于 TCF15

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:604,257-610,309 (from NCBI)

This gene has 1 transcript (splice variant), 241 orthologues and 13 paralogues. Biased expression in fat (RPKM 5.9), heart (RPKM 2.3) and 3 other tissues.

功能概要

由该基因编码的蛋白质存在于细胞核中，可能参与中胚层模式形成的早期转录调控。编码的基本螺旋-环-螺旋蛋白需要与另一种基本螺旋-环-螺旋蛋白二聚化，以实现有效的 DNA 结合。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is found in the nucleus and may be involved in the early transcriptional regulation of patterning of the mesoderm. The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding. [provided by RefSeq, Jul 2008]

TCF15 基因产物(1)

mRNA Protein Name
NM_004609.4 NP_004600.3 transcription factor 15

TCF15 蛋白结构

HLH

HLH: Helix-loop-helix DNA-binding domain (73 - 124)

  • 0
  • 100
  • 199 a.a.
蛋白主名 其他名称

transcription factor 15

TCF-15

关联疾病

疾病名称 别名
Elsahy-Waters Syndrome

Brachioskeletogenital Syndrome

Bsg Syndrome

Branchioskeletogenital Syndrome

ESWS

Hypospadias, Hypertelorism, Upper Lid Coloboma, And Mixed-Type Hearing Loss

Branchio-Skeleto-Genital Syndrome
Diffuse Gastric And Lobular Breast Cancer Syndrome

Hereditary Diffuse Gastric Cancer

HDGC

LBC

Familial Diffuse Gastric Cancer

Fdgc

Hereditary Diffuse Gastric Adenocarcinoma

Breast Cancer, Lobular

Gastric Cancer, Familial Diffuse, And Cleft Lip With Or Without Cleft Palate

DGLBC

Gastric Cancer, Hereditary Diffuse

Gastric Cancer, Familial Diffuse Breast Cancer, Lobular

Diffuse Gastric And Lobular Breast Cancer Syndrome With Or Without Cleft Lip And/Or Palate

E-Cadherin-Associated Hereditary Gastric Cancer

Familial Diffuse Cancer Of Stomach

Hereditary Diffuse Cancer Of Stomach

Gastric Cancer Familial Diffuse

Gastric Cancer Familial Diffuse And Cleft Lip With Or Without Cleft Palate

Cancer, Gastric, Hereditary Diffuse
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14300 TCF15 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TCF15 VGNC VGNC:47190
Rattus norvegicus TCF15 RGD RGD:1308464
Mus musculus TCF15 MGD MGI:104664
Bos taurus TCF15 VGNC VGNC:35687
Macaca mulatta TCF15 VGNC VGNC:78284
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