1. Gene
  2. SCGB1A1 - secretoglobin family 1A member 1 Gene

SCGB1A1 - secretoglobin family 1A member 1 Gene

中文名称:分泌珠蛋白家族 1A 成员 1

种属: Homo sapiens

同用名: UGB; UP1; CC10; CC16; CCSP; UP-1; CCPBP

基因 ID: 7356 | 基因类型: protein coding

关于 SCGB1A1

Cytogenetic location: 11q12.3 Genomic coordinates (GRCh38): 11:62,419,033-62,423,195 (from NCBI)

This gene has 2 transcripts (splice variants), 63 orthologues and 2 paralogues. Restricted expression toward lung (RPKM 1367.3).

功能概要

该基因编码小分泌蛋白的分泌珠蛋白家族的成员。编码的蛋白质涉及许多功能,包括抗炎、抑制磷脂酶 A2 和隔离疏水配体。该基因的缺陷与哮喘易感性有关。[RefSeq 提供,2010 年 5 月]

This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of Phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010]

SCGB1A1 基因产物(1)

mRNA Protein Name
NM_003357.5 NP_003348.1 uteroglobin precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16423471 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
21805676 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SCGB1A1 蛋白结构

Uteroglobin

Uteroglobin: Uteroglobin family (24 - 90)

  • 0
  • 91 a.a.
蛋白主名 其他名称

uteroglobin

Uteroglobin (club-cell specific 10-kD protein)

SCGB1A1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SCGB1A1 P11684 AQP6 Homo sapiens Q13520
Validated Y2H
32296183
种属内
SCGB1A1 P11684 AQP6 Homo sapiens Q13520
Y2H Array
32296183
种属内
SCGB1A1 P11684 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
种属内
SCGB1A1 P11684 GATM Homo sapiens P50440
Validated Y2H
32814053
种属内
SCGB1A1 P11684 GATM Homo sapiens P50440
Y2H Array
32814053
种属内
SCGB1A1 P11684 GATM Homo sapiens P50440
Y2H Pooling
32814053
种属内
SCGB1A1 P11684 ACTA2 Homo sapiens P62736
Anti Tag CoIP
33961781
种属内
SCGB1A1 P11684 ACTA2 Homo sapiens P62736
Anti Tag CoIP
28514442
种属内
SCGB1A1 P11684 HSF1 Homo sapiens Q00613
Y2H Pooling
32814053
种属内
SCGB1A1 P11684 HSF1 Homo sapiens Q00613
Validated Y2H
32814053
种属内
SCGB1A1 P11684 HSF1 Homo sapiens Q00613
Y2H Array
32814053
种属内
SCGB1A1 P11684 TMEM43 Homo sapiens Q9BTV4
Y2H Array
32296183
种属内
SCGB1A1 P11684 TMEM43 Homo sapiens Q9BTV4
Y2H Prey Pooling
32296183
种属内
SCGB1A1 P11684 TMEM43 Homo sapiens Q9BTV4
Validated Y2H
32296183
种属内
SCGB1A1 P11684 TRIM32 Homo sapiens Q13049
Validated Y2H
32296183
种属内
SCGB1A1 P11684 TRIM32 Homo sapiens Q13049
Y2H Array
31515488
种属内
SCGB1A1 P11684 TRIM32 Homo sapiens Q13049
Y2H Prey Pooling
32296183
种属内
SCGB1A1 P11684 TRIM32 Homo sapiens Q13049
Y2H Array
25416956
种属内
SCGB1A1 P11684 TRIM32 Homo sapiens Q13049
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 SCGB1A1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71107 Uteroglobin/SCGB1A1 Protein, Human (HEK293, His) P11684 (E22-N91) ≥95%
HY-P71933 Uteroglobin/SCGB1A1 Protein, Human P11684 (E22-N91) ≥95%

关联疾病

疾病名称 别名
Silicosis

Silicotuberculosis

Acute Silicosis

Chronic Silicosis

Pneumoconiosis Due To Silicates

Silica Pneumoconiosis

Silicotic Fibrosis Of Lung

Accelerated Silicosis

Experimental Silicosis

Bronchopulmonary Dysplasia

Bpd

Bronchiolitis Obliterans

Bronchiolitis Fibrosa Obliterans

Obliterative Bronchiolitis

Bronchiolitis Exudativa

Bronchiolitis, Exudative

Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus

Lung Benign Neoplasm

Lung Neoplasms

Tumor Of The Lung

Lung Tumor

Meconium Aspiration Syndrome

Neonatal Aspiration Of Meconium

Meconium Aspiration

Mas

Meconium Aspiration Syndrome Of Newborn

Meconium Inhalation

Mas - [Meconium Aspiration Syndrome]

Meconium Aspiration Nos

Meconium Aspiration Syndrome Nos

Meconium Pneumonitis

Meconium Stained Liqueur Aspiration

Respiratory Failure

Acute Respiratory Failure

Chronic Respiratory Failure

Respiratory Insufficiency

Acute-On-Chronic Respiratory Failure

Respiratory Disease

Acute And Chronic Respiratory Failure

Respiratory Insufficiency/Failure

Chronic Respiratory Disease

Pulmonary Valve Insufficiency

Chronic Disease Of Respiratory System

Respiration Disorders

Respiratory Tract Diseases

Lung Failure Nos

Pulmonary Failure

Arf - [Acute Respiratory Failure]

Acute Respiratory Insufficiency

Acute Pulmonary Insufficiency

Acute Respiration Failure

Chronic Respiration Failure

Maple Bark Strippers' Lung

Alveolitis Due To Cryptostroma Corticale

Maple-Bark Strippers' Lung

Maple Bark Disease

Maple Bark Stripper'S Disease

Maple Bark Stripper'S Lung

Maple Bark-Strippers' Lung

Cryptostromosis

Maple-Bark Disease

Maple-Bark Strippers' Disease

Rhinitis

Runny Nose

Alveoli Adenoma

Alveolar Adenoma

Adenoma Of Alveoli

Adenoma Of The Alveoli

Bronchial Benign Neoplasm

Bronchus Neoplasm

Neoplasm Of Bronchus

Bronchial Neoplasms

Bronchial Neoplasm

Iga Glomerulonephritis

Iga Nephropathy

Glomerulonephritis, Iga

Berger'S Iga Or Igg Nephropathy

Focal Glomerulonephritis

Primary Iga Nephropathy

Segmental Glomerulonephritis

Berger Disease

Berger'S Disease

Igan

Nephritis, Iga Type

Nephropathy Iga

Glomerulonephritis Focal

Iga Nephropathy, Susceptibility To

Primary Immunoglobulin A Nephropathy

Toxic Pneumonitis

Acute Chemical Fume Pulmonary Edema

Acute Chemical Pulmonary Edema

Acute Pulmonary Edema Due To Fumes And/Or Vapors

Pneumonia

Acute Pneumonia

Pneumonias

Infectious Pneumonia

Pn - [Pneumonia]

Lobar Pneumonia Nos

Multifocal Pneumonia

Orthostatic Pneumonia

Pneumonia Nos

Chronic Pneumonia Nos

Atypical Pneumonia

Passive Pneumonia

Purulent Pneumonia

Interstitial Lobar Pneumonia

Pneumonia, Unspecified

Pneumonia Due To Chlamydia

Pneumonia Due To Chlamydia Pneumoniae

Pneumonia Due To E. Coli

Escherichia Coli Lobar Pneumonia

Pneumonia Due To H. Influenzae

Pneumonia Due To Hemophilus Influenzae

Bronchopneumonia Due To H. Influenzae

Haemophilus Influenzae Lobar Pneumonia

Bronchopneumonia Due To Hemophilus Influenzae

Pseudomonal Pneumonia

Pseudomonas Pneumonia

Pseudomonas Lobar Pneumonia

Staphylococcal Pneumonia

Staphylococcus Pneumonia

Acute Staphylococcal Pneumonia

Staphylococcal Double Pneumonia

Staphylococcal Lobar Pneumonia

Staphylococcal Purulent Pneumonia

Staphylococcal Bronchopneumonia

Pneumococcal Pneumonia

Pneumococcus Pneumonia

Bronchopneumonia Due To S. Pneumoniae

Pneumococcal Lobar Pneumonia

Streptococcal Pneumoniae Pneumonia

Streptococcus Pneumoniae Lobar Pneumonia

Pyemic Pneumococcal Embolism With Pneumonia

Bronchopneumonia Due To Streptococcus Pneumoniae

Pneumonia Due To Streptococcus, Group B

Group B Streptococcal Pneumonia

Adenovirus Pneumonia

Adenoviral Pneumonia

Adenovirus Viral Pneumonia

Pneumonia Respiratory Syncytial Viral

Parainfluenza Viral Pneumonia

Parainfluenzal Pneumonia

Parainfluenza Virus Pneumonia

Human Metapneumovirus Pneumonia

Human Metapneumovirus Infection Resulting In Pneumonia

Pneumocystis Pneumonia

Plasma Cells Pneumonia

Sarcoidosis 1

Sarcoidosis

Boeck Sarcoid

Besnier-Boeck-Schaumann Disease

SS1

Sarcoidosis, Susceptibility To, 1

Lymphogranulomatosis

Hodgkin Disease

Boeck'S Disease

Boeck'S Sarcoid

Schaumann'S Disease Or Syndrome

Hutchinson-Boeck Disease Or Syndrome

Allergic Asthma

Atopic Asthma

Extrinsic Asthma

Extrinsic Asthma With Acute Exacerbation

Extrinsic Asthma With Status Asthmaticus

Asthma Allergic

Atopic Asthma, Susceptibility To

Ige-Mediated Allergic Asthma

Allergen-Induced Asthma

Allergic Asthma Without Stated Status Asthmaticus

Predominantly Allergic Asthma Without Stated Status Asthmaticus

Predominantly Allergic Asthma

Allergic Asthma Nos

Catarrh With Asthma

Allergic Bronchitis Nos

Extrinsic Allergic Asthma

Predominantly Allergic Asthma With Stated Status Asthmaticus

Allergic Rhinitis

Hay Fever

Allergic Rhinitis, Susceptibility To

ALRH

Atopic Rhinitis

Seasonal Allergic Rhinitis

Non-Seasonal Allergic Rhinitis

Perenial Allergic Rhinitis

Pollenosis

Rhinitis Allergic Seasonal

Rhinitis, Allergic, Perennial

Allergic Rhinitis, Cause Unspecified

Pollinosis

Pollen Allergy

Allergy Nos Due To Pollen

Summer Catarrh

Other Seasonal Allergic Rhinitis

Glomerulonephritis

Bright'S Disease

Adult Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome

Ards

Non-Cardiogenic Pulmonary Edema

Acute Lung Injury

Respiratory Distress Syndrome, Adult

Shock Lung

Acute Respiratory Distress

Respiratory Distress Syndrome

Adult Rds

Ali

Increased-Permeability Pulmonary Edema

Stiff Lung

Respiratory Distress Syndrome Adult

Respiratory System Benign Neoplasm
Pulmonary Edema
Exercise-Induced Bronchoconstriction

Exercise-Induced Asthma

Asthma Exercise-Induced

Lung Adenoma

Adenoma Of Lung

Pulmonary Adenoma

Pulmonary Disease, Chronic Obstructive

Chronic Obstructive Pulmonary Disease

COPD

Pulmonary Disease, Chronic Obstructive, Severe Early-Onset

Chronic Obstructive Lung Disease

Chronic Obstructive Airway Disease

Pulmonary Disease, Chronic Obstructive, Susceptibility To

Cold

Severe Early-Onset Chronic Obstructive Pulmonary Disease

Pulmonary Disease Chronic Obstructive

Pulmonary Disease, Obstructive, Chronic, Susceptibility To

Chronic Obstructive Pulmonary Disease Of Horses

Common Cold

Upper Respiratory Infections

Copd - [Chronic Obstructive Pulmonary Disease]

Coad - [Chronic Obstructive Airways Disease]

Cold - [Chronic Obstructive Lung Disease]

Chronic Airway Disease Nos

Chronic Airways Limitation, Unspecified

Chronic Obstructed Airway, Unspecified

Chronic Obstructive Airway Disease, Unspecified

Chronic Obstructive Airway, Unspecified

Obstructive Lung Disease Nos

Chronic Obstructive Lung Disease Nos

Chronic Obstructive Lung Nos

Obstructive Pulmonary Disease Nos

Exacerbation Copd Nos

Acute Exacerbation Copd

Subleukemic Leukemia

Aleukemic Leukemia Cutis

Leukemia Subleukemic

Cork-Handlers' Disease

Suberosis

Cork-Handlers' Disease Or Lung

Cork-Handlers' Lung

Corkhandler Disease

Corkworker Lung

Corkhandler Hypersensitivity Pneumonitis

Cork-Handler Disease

Cork-Handler Lung

Malt Worker'S Lung

Alveolitis Due To Aspergillus Clavatus

Malt Worker Lung

Malt Workers' Lung

Malt-Workers' Lung

Malt Fever

Malt House Workers' Cough

Malt-Workers' Alveolitis

Malt-Workers' Lung Disease

Alveolitis Due To Aspergillus Fumigatus

Extrinsic Allergic Alveolitis Due To Aspergillus Spp

Anthracosilicosis
Lung Disease

Lung Diseases

Disorder Of Lung

Abnormality Of The Lung

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Interstitial Lung Disease 2

Idiopathic Pulmonary Fibrosis

Ipf

Fibrocystic Pulmonary Dysplasia

Pulmonary Fibrosis, Idiopathic

Pulmonary Fibrosis, Idiopathic, Susceptibility To

Cryptogenic Fibrosing Alveolitis

ILD2

Idiopathic Pulmonary Fibrosis, Familial

Fibrosing Alveolitis, Cryptogenic

Uip

Fibrosing Alveolitis

Interstitial Pneumonitis, Usual

Familial Idiopathic Pulmonary Fibrosis

Idiopathic Fibrosing Alveolitis, Chronic Form

Usual Interstitial Pneumonia

Fibrosing Alveolitis Cryptogenic

Hamman-Rich Disease

Idiopathic Pulmonary Fibrosis Familial

Interstitial Pneumonitis Usual

Fibrosis Idiopathic Pulmonary

Fibrosis, Pulmonary, Idiopathic

Hamman-Rich Syndrome

Chronic Idiopathic Pulmonary Fibrosis

Acute Interstitial Pneumonia

Interstitial Pulmonary Fibrosis

Ipf - [Idiopathic Pulmonary Fibrosis]

Idiopathic Lung Fibrosis

Fibrosing Lung Disease

Pulmonary Fibrosis Nos

Fibrosing Pneumonitis

Granulomatous Endometritis
Neonatal Respiratory Failure

Respiratory Failure Of Newborn

Inadequate Pulmonary Ventilation Of Newborn

Newborn Lung Insufficiency

Newborn Pulmonary Function Inadequate

Newborn Pulmonary Insufficiency

Newborn Respiration Failure

Newborn Respiratory Insufficiency

Respiratory Insufficiency Syndrome Of Newborn

Endometrial Cancer

Endometrial Carcinoma

Endometrial Neoplasm

Malignant Neoplasm Of Endometrium

Endometrioid Carcinoma

Endometrial Neoplasms

Carcinoma, Endometrioid

Endometrial Cancer, Familial

Endometrial Carcinoma, Somatic

Endometrial Cancer, Susceptibility To

Endometrial Ca

Malignant Endometrial Neoplasm

Neoplasm Of Endometrium

Primary Malignant Neoplasm Of Endometrium

Tumor Of Endometrium

Carcinoma Of The Endometrium

Endometrioid Carcinoma Of Female Reproductive System

ENDMC

Carcinoma Endometrioid

Endometrial Cancers

Cancer, Endometrial

Uterine Corpus Cancer

Intrinsic Asthma

Non-Atopic Asthma

Papillary Adenoma

Glandular Papilloma

Adenoma

Lung Cancer Susceptibility 3

Lung Adenocarcinoma

Adenocarcinoma Of Lung

LNCR3

Adenocarcinoma Of Lung, Susceptibility To

Bronchogenic Lung Adenocarcinoma

Nonsmall Cell Adenocarcinoma

Adenocarcinoma Lung

Lung Adenocarcinomas

Non-Small Cell Adenocarcinoma

Bronchial Disease

Bronchial Diseases

Bronchial Disorders

Bronchial Spasm

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SCGB1A1 RGD RGD:3934
Felis catus SCGB1A1 VGNC VGNC:64911
Bos taurus SCGB1A1 VGNC VGNC:34335
Macaca mulatta SCGB1A1 VGNC VGNC:77004
Canis familiaris SCGB1A1 VGNC VGNC:45908
Mus musculus SCGB1A1 MGD MGI:98919
Others SCGB1A1 NCBI