1. Gene
  2. FASTKD1 - FAST kinase domains 1 Gene

FASTKD1 - FAST kinase domains 1 Gene

中文名称:FAST 激酶结构域 1

种属: Homo sapiens

基因 ID: 79675 | 基因类型: protein coding

关于 FASTKD1

Cytogenetic location: 2q31.1 Genomic coordinates (GRCh38): 2:169,528,508-169,573,865 (from NCBI)

This gene has 10 transcripts (splice variants), 192 orthologues and 5 paralogues. Ubiquitous expression in heart (RPKM 4.3), duodenum (RPKM 3.9) and 25 other tissues.

功能概要

启用 RNA 结合活性。参与线粒体 RNA 代谢过程和线粒体 mRNA 稳定性的调节。位于线粒体中。 [由基因组资源联盟提供,2022 年 4 月]

Enables RNA binding activity. Involved in mitochondrial RNA metabolic process and regulation of mitochondrial mRNA stability. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

FASTKD1 基因产物(5)

mRNA Protein Name
NM_001281476.3 NP_001268405.1 FAST kinase domain-containing protein 1, mitochondrial isoform 2
NM_001322046.2 NP_001308975.1 FAST kinase domain-containing protein 1, mitochondrial isoform 1
NM_001322048.2 NP_001308977.1 FAST kinase domain-containing protein 1, mitochondrial isoform 3
NM_001322049.2 NP_001308978.1 FAST kinase domain-containing protein 1, mitochondrial isoform 4
NM_024622.6 NP_078898.3 FAST kinase domain-containing protein 1, mitochondrial isoform 1

FASTKD1 蛋白结构

FAST_1

FAST_1: FAST kinase-like protein, subdomain 1 (575 - 643)

FAST_2

FAST_2: FAST kinase-like protein, subdomain 2 (657 - 743)

RAP

RAP: RAP domain (781 - 837)

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  • 847 a.a.
蛋白主名 其他名称

FAST kinase domain-containing protein 1, mitochondrial

FASTKD1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
FASTKD1 Q53R41 EIF2S3 Homo sapiens P41091
Y2H Array
32814053
种属内
FASTKD1 Q53R41 EIF2S3 Homo sapiens P41091
Y2H Pooling
32814053
种属内
FASTKD1 Q53R41 EIF2S3 Homo sapiens P41091
Validated Y2H
32814053
种属内
FASTKD1 Q53R41 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
种属内
FASTKD1 Q53R41 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
种属内
FASTKD1 Q53R41 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
种属内
FASTKD1 Q53R41 KIF1B Homo sapiens O60333-2
Y2H Pooling
32814053
种属内
FASTKD1 Q53R41 KIF1B Homo sapiens O60333-2
Validated Y2H
32814053
种属内
FASTKD1 Q53R41 KIF1B Homo sapiens O60333-2
Y2H Array
32814053
种属内
FASTKD1 Q53R41 ST13 Homo sapiens Q9P1I4
Y2H Pooling
32814053
种属内
FASTKD1 Q53R41 ST13 Homo sapiens Q9P1I4
Validated Y2H
32814053
种属内
FASTKD1 Q53R41 ST13 Homo sapiens Q9P1I4
Y2H Array
32814053
种属内
FASTKD1 Q53R41 HSPA2 Homo sapiens P54652
Validated Y2H
32814053
种属内
FASTKD1 Q53R41 HSPA2 Homo sapiens P54652
Y2H Array
32814053
种属内
FASTKD1 Q53R41 HSPA2 Homo sapiens P54652
Y2H Pooling
32814053
种属内
FASTKD1 Q53R41 P4HB Homo sapiens P07237
Validated Y2H
32814053
种属内
FASTKD1 Q53R41 P4HB Homo sapiens P07237
Y2H Array
32814053
种属内
FASTKD1 Q53R41 P4HB Homo sapiens P07237
Y2H Pooling
32814053
种属内
FASTKD1 Q53R41 NEFL Homo sapiens P07196
Y2H Pooling
32814053
种属内
FASTKD1 Q53R41 NEFL Homo sapiens P07196
Validated Y2H
32814053
种属内
FASTKD1 Q53R41 NEFL Homo sapiens P07196
Y2H Array
32814053
种属内
FASTKD1 Q53R41 WFS1 Homo sapiens O76024
Validated Y2H
32814053
种属内
FASTKD1 Q53R41 WFS1 Homo sapiens O76024
Y2H Array
32814053
种属内
FASTKD1 Q53R41 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
种属内
FASTKD1 Q53R41 GFAP Homo sapiens P14136
Y2H Array
32814053
种属内
FASTKD1 Q53R41 GFAP Homo sapiens P14136
Y2H Pooling
32814053
种属内
FASTKD1 Q53R41 GFAP Homo sapiens P14136
Validated Y2H
32814053
种属内
FASTKD1 Q53R41 GRN Homo sapiens P28799
Validated Y2H
32814053
种属内
FASTKD1 Q53R41 GRN Homo sapiens P28799
Y2H Pooling
32814053
种属内
FASTKD1 Q53R41 GRN Homo sapiens P28799
Y2H Array
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Glaucoma 1, Open Angle, B

GLC1B

Glaucoma 1b, Primary Open Angle, Adult Onset

Mitochondrial Encephalomyopathy

Mitochondrial Encephalomyopathies

Encephalomyopathy, Mitochondrial

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus FASTKD1 VGNC VGNC:28873
Rattus norvegicus FASTKD1 RGD RGD:1563531
Canis familiaris FASTKD1 VGNC VGNC:40738
Felis catus FASTKD1 VGNC VGNC:62154
Mus musculus FASTKD1 MGD MGI:2444596
Macaca mulatta FASTKD1 VGNC VGNC:72580