VTCN1 - V-set domain containing T cell activation inhibitor 1 Gene

中文名称：含 V 组结构域的 T 细胞激活抑制剂 1

种属: Homo sapiens

同用名: B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291

关于 VTCN1

功能概要

该基因编码属于 B7 共刺激蛋白家族的一种蛋白质。该家族中的蛋白质存在于抗原呈递细胞的表面，并与与 T 细胞表面受体结合的配体相互作用。研究表明，高水平的编码蛋白与肿瘤进展相关。该基因的假基因位于 20 号染色体上。已发现该基因编码不同亚型的多个转录变体。[RefSeq 提供，2011 年 12 月]

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]