2. Gene
  3. MOB3B - MOB kinase activator 3B Gene

MOB3B - MOB kinase activator 3B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：MOB 激酶激活因子 3B

种属: Homo sapiens

同用名: MOB1D; C9orf35; MOBKL2B

基因 ID: 79817 | 基因类型: protein coding

关于 MOB3B

Cytogenetic location: 9p21.2 Genomic coordinates (GRCh38): 9:27,325,209-27,529,814 (from NCBI)

This gene has 2 transcripts (splice variants), 150 orthologues and 6 paralogues. Ubiquitous expression in ovary (RPKM 14.2), duodenum (RPKM 9.8) and 20 other tissues.

功能概要

该基因编码的蛋白质与酵母 Mob1 蛋白质具有相似性。酵母 Mob1 结合 Mps1p，这是一种对纺锤体极体复制和有丝分裂检查点调节必不可少的蛋白激酶。该基因位于与干扰素κ前体 (IFNK) 基因相反的链上。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul 2008]

MOB3B 基因产物(1)

mRNA Protein Name
NM_024761.5 NP_079037.3 MOB kinase activator 3B
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of hippo signaling IMP
IMP: 通过突变表型推断
28792927 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MOB3B 蛋白结构

Mob1_phocein

Mob1_phocein: Mob1/phocein family (31 - 208)

  • 0
  • 100
  • 200
  • 216 a.a.
蛋白主名 其他名称

MOB kinase activator 3B

MOB kinase activator-like 2B

关联疾病

疾病名称 别名
Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1

FTDALS1

Frontotemporal Dementia And/Or Motor Neuron Disease

Ftdmnd

Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia

Alsftd

Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis

Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis-1

Frontotemporal Dementia With Motor Neuron Disease

Ftdals

Ftd-Als

Ftd-Mnd

Frontotemporal Dementia With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis With Frontotemporal Dementia 1

Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

Dementia, Frontotemporal, And/Or Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia 1

Frontotemporal Lobar Degeneration

Grn-Related Frontotemporal Dementia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08576 MOB3B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris MOB3B VGNC VGNC:43303
Felis catus MOB3B VGNC VGNC:63547
Mus musculus MOB3B MGD MGI:2664539
Rattus norvegicus MOB3B RGD RGD:1560696
Bos taurus MOB3B VGNC VGNC:31545
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