2. Gene
  3. Hcar2 - hydroxycarboxylic acid receptor 2 Gene

Hcar2 - hydroxycarboxylic acid receptor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：羟基羧酸受体 2

种属: Mus musculus

同用名: HM74; Pumag; Niacr1; PUMA-G; mHM74b; Gpr109a; Gpr109b

基因 ID: 80885 | 基因类型: protein coding

关于 Hcar2

Chromosome 5: 124,001,633-124,003,562 reverse strand.GRCm39:CM000998.3

This gene has 1 transcript (splice variant), 164 orthologues, 13 paralogues and is associated with 5 phenotypes.

功能概要

该基因编码的蛋白可启动 G 蛋白偶联受体活性； GTP结合活性；和嘌呤核苷酸受体活性。参与 G 蛋白偶联受体信号通路。是膜的组成部分。在膜中有活性。在胚胎中表达。与包括 HCAR3（羟基羧酸受体 3）在内的几个人类基因同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled receptor activity; GTP binding activity; and purinergic nucleotide receptor activity. Involved in G protein-coupled receptor signaling pathway. Is integral component of membrane. Is active in membrane. Is expressed in embryo. Orthologous to several human genes including HCAR3 (hydroxycarboxylic acid receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Hcar2 基因产物(1)

mRNA Protein Name
NM_030701.3 NP_109626.1 hydroxycarboxylic acid receptor 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IDA
IDA: 通过直接分析推断
19047060 MGI
enables GTP binding IDA
IDA: 通过直接分析推断
12646212 MGI
enables purinergic nucleotide receptor activity IDA
IDA: 通过直接分析推断
12646212 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
19047060 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in membrane IDA
IDA: 通过直接分析推断
19047060 MGI
located in membrane IDA
IDA: 通过直接分析推断
12646212 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Hcar2 蛋白结构

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (24 - 301)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (25 - 51)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (58 - 83)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (96 - 126)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (138 - 160)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (181 - 210)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (220 - 250)

7tmA_HCAR1-3

7tmA_HCAR1-3: cd15201 (269 - 294)

  • 0
  • 100
  • 200
  • 300
  • 360 a.a.
蛋白主名 其他名称

hydroxycarboxylic acid receptor 2

G protein-coupled receptor 109A

G protein-coupled receptor 109B

G-protein coupled receptor 109

G-protein coupled receptor HM74

interferon-gamma inducible gene, Puma-g

niacin receptor 1

nicotinic acid receptor

putative seven transmembrane spanning receptor

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06038 HCAR2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-156025 HCAR2 agonist 1 / 否
HY-RS06039 Hcar2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06040 Hcar2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hcar2 NCBI NCBI:338442
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