Bmpr1a - bone morphogenetic protein receptor type 1A Gene

中文名称：骨形态发生蛋白受体 1A型

种属: Rattus norvegicus

关于 Bmpr1a

功能概要

预计该基因编码的蛋白可启动多种功能，包括 ATP 绑定活动；酶活化剂活性；和跨膜受体蛋白丝氨酸/苏氨酸激酶活性。预计参与多个过程，包括循环系统发育；细胞群增殖的正向调节；跨膜受体蛋白丝氨酸/苏氨酸激酶信号通路的正调控。预计在几个过程的上游或内部起作用，包括动物器官发育；肢体形态发生；和区域化。位于树突和神经细胞体中。该基因的人类直系同源基因与遗传性混合性息肉病综合征 2 相关；肠道疾病；和幼年息肉病综合征。与人类 BMPR1A（1A 型骨形态发生蛋白受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including ATP binding activity; Enzyme activator activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in several processes, including circulatory system development; positive regulation of cell population proliferation; and positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to act upstream of or within several processes, including animal organ development; limb morphogenesis; and regionalization. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in hereditary mixed polyposis syndrome 2; intestinal disease; and juvenile polyposis syndrome. Orthologous to human BMPR1A (bone morphogenetic protein receptor type 1A). [provided by Alliance of Genome Resources, Apr 2022]