1. Gene
  2. SLCO5A1 - solute carrier organic anion transporter family member 5A1 Gene

SLCO5A1 - solute carrier organic anion transporter family member 5A1 Gene

中文名称:溶质载体有机阴离子转运家族成员 5A1

种属: Homo sapiens

同用名: OATPJ; OATP-J; OATP5A1; OATPRP4; OATP-RP4; SLC21A15

基因 ID: 81796 | 基因类型: protein coding

关于 SLCO5A1

Cytogenetic location: 8q13.3 Genomic coordinates (GRCh38): 8:69,667,046-69,834,978 (from NCBI)

This gene has 8 transcripts (splice variants), 277 orthologues and 10 paralogues. Ubiquitous expression in small intestine (RPKM 68.6), ovary (RPKM 66.6) and 25 other tissues.

功能概要

该基因编码 12 个跨膜结构域的蛋白质,该蛋白质是溶质载体有机阴离子转运蛋白超家族的成员。可变剪接导致多个转录本变体。[RefSeq 提供,2009 年 3 月]

This gene encodes a 12 transmembrane domain protein that is a member of the solute carrier organic anion transporter superfamily. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

SLCO5A1 基因产物(3)

mRNA Protein Name
NM_001146008.2 NP_001139480.1 solute carrier organic anion transporter family member 5A1 isoform 2
NM_001146009.1 NP_001139481.1 solute carrier organic anion transporter family member 5A1 isoform 3
NM_030958.3 NP_112220.2 solute carrier organic anion transporter family member 5A1 isoform 1
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
21278488 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SLCO5A1 蛋白结构

OATP

OATP: Organic Anion Transporter Polypeptide (OATP) family (128 - 735)

Kazal_2

Kazal_2: Kazal-type serine protease inhibitor domain (561 - 603)

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  • 800
  • 848 a.a.
蛋白主名 其他名称

solute carrier organic anion transporter family member 5A1

organic anion transporter polypeptide-related protein 4

SLCO5A1 抗体

目录号 产品名 应用 反应物种
HY-P82246 SLCO5A1 Antibody (YA1991) WB, IHC-P Human, Mouse

关联疾病

疾病名称 别名
Mesomelia-Synostoses Syndrome

Mesomelic Dysplasia With Acral Synostoses, Verloes-David-Pfeiffer Type

Verloes-David Syndrome

Chromosome 8q13 Deletion Syndrome

Mesomelic Dysplasia, Syndromic

Dominant Mesomelic Shortness Of Stature With Acral Synostoses, Umbilical Anomalies, And Soft Palate Agenesis

Mesomelia Synostoses

8q13 Microdeletion Syndrome

Del(8)Q(13)

Mesomelia-Synostoses Syndrome, Verloes-David-Pfeiffer Type

Monosomy 8q13

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus SLCO5A1 MGD MGI:2443431
Felis catus SLCO5A1 VGNC VGNC:65449
Macaca mulatta SLCO5A1 VGNC VGNC:77736
Bos taurus SLCO5A1 VGNC VGNC:34956
Rattus norvegicus SLCO5A1 RGD RGD:1307132
Canis familiaris SLCO5A1 VGNC VGNC:46500