RAB34 - RAB34, member RAS oncogene family Gene

中文名称：RAB34，RAS 致癌基因家族成员

种属: Homo sapiens

同用名: RAH; NARR; RAB39

关于 RAB34

功能概要

该基因编码属于 RAB 蛋白家族的一种蛋白，RAB 蛋白是参与蛋白转运的小 GTP 酶。该家族成员是分泌途径的高尔基体结合成员，参与溶酶体的重新定位和巨胞饮作用的激活。该基因的可变剪接导致多个转录变体。选择性剪接的转录物变体产生九个氨基酸残基重复 (NARR) 蛋白，这是一种功能不同的核仁蛋白，由不同的阅读框产生。[RefSeq 提供，2016 年 12 月]

This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. An alternatively spliced transcript variant produces the nine-amino acid residue-repeats (NARR) protein, which is a functionally distinct nucleolar protein resulting from a different reading frame. [provided by RefSeq, Dec 2016]