1. Gene
  2. FUT10 - fucosyltransferase 10 Gene

FUT10 - fucosyltransferase 10 Gene

中文名称:岩藻糖基转移酶 10

种属: Homo sapiens

同用名: FUCTX

基因 ID: 84750 | 基因类型: protein coding

关于 FUT10

Cytogenetic location: 8p12 Genomic coordinates (GRCh38): 8:33,308,061-33,473,146 (from NCBI)

This gene has 11 transcripts (splice variants), 249 orthologues and 7 paralogues. Ubiquitous expression in ovary (RPKM 2.0), placenta (RPKM 1.5) and 25 other tissues.

功能概要

预计会启用 alpha- (1->3) -岩藻糖基转移酶活性。预计参与岩藻糖基化。预测作用于大脑皮层上游或内部径向定向细胞迁移和神经元干细胞群维持。位于高尔基体;内质网;和核质。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to act upstream of or within cerebral cortex radially oriented cell migration and neuronal stem cell population maintenance. Located in Golgi apparatus; endoplasmic reticulum; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

FUT10 基因产物(1)

mRNA Protein Name
NM_032664.3 NP_116053.3 alpha-(1,3)-fucosyltransferase 10
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fucosyltransferase activity IDA
IDA: 通过直接分析推断
19088067 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in N-glycan fucosylation IDA
IDA: 通过直接分析推断
19088067 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

FUT10 蛋白结构

Glyco_transf_10

Glyco_transf_10: Glycosyltransferase family 10 (fucosyltransferase) C-term (13 - 398)

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  • 479 a.a.
蛋白主名 其他名称

alpha-(1,3)-fucosyltransferase 10

alpha (1,3) fucosyltransferase

重组 FUT10 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76941 FUT10 Protein, Human (HEK293, His) Q6P4F1-1 (L32-D479) ≥95%

关联疾病

疾病名称 别名
Dowling-Degos Disease

Reticular Pigment Anomaly Of Flexures

Dark Dot Disease

Reticulate Acropigmentation Of Kitamura

Dowling-Degos Kitamura Disease

Kitamura Reticulate Acropigmentation

Ddd

Dowling-Degos-Kitamura Disease

Reticular Pigmented Anomaly Of Flexures

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris FUT10 VGNC VGNC:41012
Macaca mulatta FUT10 VGNC VGNC:72745
Bos taurus FUT10 VGNC VGNC:29148
Felis catus FUT10 VGNC VGNC:62392
Rattus norvegicus FUT10 RGD RGD:1359164
Mus musculus FUT10 MGD MGI:2384748
Others FUT10 NCBI