PPFIA4 - PTPRF interacting protein alpha 4 Gene

中文名称：PTPRF 相互作用蛋白 alpha 4

种属: Homo sapiens

基因 ID: 8497 | 基因类型: protein coding

关于 PPFIA4

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:203,026,491-203,078,736 (from NCBI)

This gene has 15 transcripts (splice variants), 210 orthologues and 5 paralogues. Biased expression in brain (RPKM 8.9), heart (RPKM 8.4) and 10 other tissues.

功能概要

PPFIA4 或 liprin-alpha-4 属于 liprin-alpha 基因家族。参见 liprin-alpha-1 (LIP1 或 PPFIA1；MIM 611054) 了解 liprins 的背景。[OMIM 提供，2008 年 3 月]

PPFIA4, or liprin-alpha-4, belongs to the liprin-alpha gene family. See liprin-alpha-1 (LIP1, or PPFIA1; MIM 611054) for background on liprins.[supplied by OMIM, Mar 2008]

PPFIA4 基因产物(10)

mRNA	Protein	Name
NM_001304331.2	NP_001291260.1	liprin-alpha-4 isoform 1
NM_001304332.2	NP_001291261.1	liprin-alpha-4 isoform 2
NM_001393950.1	NP_001380879.1	liprin-alpha-4 isoform 3
NM_001393951.1	NP_001380880.1	liprin-alpha-4 isoform 4
NM_001393952.1	NP_001380881.1	liprin-alpha-4 isoform 5
NM_001393953.1	NP_001380882.1	liprin-alpha-4 isoform 6
NM_001393954.1	NP_001380883.1	liprin-alpha-4 isoform 7
NM_001393955.1	NP_001380884.1	liprin-alpha-4 isoform 8
NM_001393956.1	NP_001380885.1	liprin-alpha-4 isoform 9
NM_001393957.1	NP_001380886.1	liprin-alpha-4 isoform 10

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	12923177	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PPFIA4 蛋白结构

SAM_1

SAM_2

0
200
400
600
800
1000
1185 a.a.

蛋白主名

其他名称

liprin-alpha-4

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4

关联疾病

疾病名称

别名

Congenital Lipomatous Overgrowth, Vascular Malformations, And Epidermal Nevi

Cloves Syndrome	Clove Syndrome
Congenital Lipomatous Overgrowth, Vascular Malformations, Epidermal Nevi, And Skeletal/Spinal Abnormalities	Clove Syndrome, Somatic
Nevus	Congenital Lipomatous Overgrowth - Vascular Malformation - Epidermal Nevi
Congenital Lipomatous Overgrowth-Vascular Malformation-Epidermal Nevi-Skeletal Anomaly Syndrome	Congenital Lipomatous Overgrowth-Vascular Malformation-Epidermal Nevi-Spinal Anomaly Syndrome
CLOVE	Congenital Lipomatous Overgrowth Vascular Malformations Epidermal Nevi And Skeletal/Spinal Abnormalities
Congenital Arteriovenous Malformation	Arteriovenous Hemangioma
Melanocytic Nevus	Benign Melanocytic Nevus

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS10942	PPFIA4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	PPFIA4	VGNC	VGNC:33192
Rattus norvegicus	PPFIA4	RGD	RGD:620055
Canis familiaris	PPFIA4	VGNC	VGNC:44846
Mus musculus	PPFIA4	MGD	MGI:1915757
Felis catus	PPFIA4	VGNC	VGNC:68984
Macaca mulatta	PPFIA4	VGNC	VGNC:76237

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

PPFIA4 - PTPRF interacting protein alpha 4 Gene

关于 PPFIA4

功能概要

PPFIA4 基因产物(10)

PPFIA4 蛋白结构

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

PPFIA4 - PTPRF interacting protein alpha 4 Gene

关于 PPFIA4

功能概要

PPFIA4 基因产物(10)

PPFIA4 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z