1. Gene
  2. TCEAL3 - transcription elongation factor A like 3 Gene

TCEAL3 - transcription elongation factor A like 3 Gene

中文名称:转录延伸因子 A 样 3

种属: Homo sapiens

同用名: WEX8

基因 ID: 85012 | 基因类型: protein coding

关于 TCEAL3

This gene has 4 transcripts (splice variants), 120 orthologues and 8 paralogues. Ubiquitous expression in prostate (RPKM 39.3), brain (RPKM 35.9) and 25 other tissues.

功能概要

该基因编码转录延伸因子 A (SII) 样 (TCEAL) 基因家族的成员。该家族的成员包含 TFA 结构域,并且可以作为以启动子上下文相关方式调节转录的核磷蛋白发挥作用。多个家族成员位于 X 染色体上。可变剪接导致编码单个亚型的多个转录变体。[RefSeq 提供,2008 年 7 月]

This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]

TCEAL3 基因产物(2)

mRNA Protein Name
NM_001006933.2 NP_001006934.1 transcription elongation factor A protein-like 3
NM_032926.3 NP_116315.1 transcription elongation factor A protein-like 3

TCEAL3 蛋白结构

BEX

BEX: Brain expressed X-linked like family (1 - 173)

  • 0
  • 100
  • 200 a.a.
蛋白主名 其他名称

transcription elongation factor A protein-like 3

TCEA-like protein 3

关联疾病

疾病名称 别名
Severe Congenital Neutropenia 7

Autosomal Recessive Severe Congenital Neutropenia Due To Csf3r Deficiency

Scn7

Pelizaeus-Merzbacher Disease

PMD

HLD1

Pelizaeus-Merzbacher Brain Sclerosis

Leukodystrophy, Hypomyelinating, 1

Diffuse Familial Brain Sclerosis

Pelizaeus Merzbacher Brain Sclerosis

Sudanophilic Leukodystrophy, Paelizeus-Merzbacher Type

Cockayne-Pelizaeus-Merzbacher Disease

Hypomyelinating Leukodystrophy 1

Leukodystrophy, Sudanophilic

Pelizaeus Merzbacher Disease

Hypomyelinating Leukodystrophy, 1

Sudanophilic Leukodystrophy

Pelizaeus-Merzbacher Disease, Connatal Form

Connatal Pmd

Pelizaeus-Merzbacher Disease Type Ii

Severe Pmd

Null Syndrome

Plp1 Null Syndrome

Pelizaeus-Merzbacher Disease, Null Syndrome

Brain Sclerosis Diffuse Familial

Sudanophilic Leukodystrophy Paelizeus-Merzbacher Type

Leukodystrophy Hypomyelinating 1

Diffuse Cerebral Sclerosis Of Schilder

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus TCEAL3 MGD MGI:1913354
Rattus norvegicus TCEAL3 RGD RGD:1562504