1. Gene
  2. LY6D - lymphocyte antigen 6 family member D Gene

LY6D - lymphocyte antigen 6 family member D Gene

中文名称:淋巴细胞抗原 6 家族成员 D

种属: Homo sapiens

同用名: E48; Ly-6D

基因 ID: 8581 | 基因类型: protein coding

关于 LY6D

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:142,784,882-142,786,539 (from NCBI)

This gene has 4 transcripts (splice variants), 90 orthologues and 1 paralogue. Biased expression in esophagus (RPKM 212.7) and skin (RPKM 206.5).

功能概要

预计参与淋巴细胞分化。预计作用于芪类化合物的上游或响应之内。预测位于胞外区和质膜。预计在细胞表面有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in lymphocyte differentiation. Predicted to act upstream of or within response to stilbenoid. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Apr 2022]

LY6D 基因产物(1)

mRNA Protein Name
NM_003695.3 NP_003686.1 lymphocyte antigen 6D precursor

LY6D 蛋白结构

UPAR_LY6

UPAR_LY6: u-PAR/Ly-6 domain (23 - 93)

  • 0
  • 100
  • 128 a.a.
蛋白主名 其他名称

lymphocyte antigen 6D

e48 antigen

LY6D 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
LY6D Q14210 AQP6 Homo sapiens Q13520 32296183
种属内
LY6D Q14210 AQP6 Homo sapiens Q13520 32296183
种属内
LY6D Q14210 ELOVL4 Homo sapiens Q9GZR5 32296183
种属内
LY6D Q14210 ELOVL4 Homo sapiens Q9GZR5 32296183
种属内
LY6D Q14210 ELOVL4 Homo sapiens Q9GZR5 32296183
种属内
LY6D Q14210 TMEM86B Homo sapiens Q8N661 32296183
种属内
LY6D Q14210 TMEM86B Homo sapiens Q8N661 32296183
种属内
LY6D Q14210 TMEM86B Homo sapiens Q8N661 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Inflammatory Bowel Disease 27

IBD27

Squamous Cell Carcinoma, Head And Neck

Squamous Cell Carcinoma Of The Head And Neck

HNSCC

Head And Neck Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Lip

Squamous Cell Carcinoma, Head And Neck, Somatic

Carcinoma Of The Head And Neck

Squamous Cell Carcinomas Of Head And Neck

Scchn

Squamous Cell Carcinoma Of The Hypopharynx

Squamous Cell Carcinoma Of The Oropharynx

Squamous Cell Carcinoma Of Salivary Glands

Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses

Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses

Squamous Cell Carcinoma Of The Oral Cavity

Squamous Cell Carcinoma Of The Lip

Carcinoma, Squamous Cell Of Head And Neck

Lip Squamous Cell Carcinoma

Carcinoma, Squamous Cell, Head And Neck

Salivary Gland Squamous Cell Carcinoma

Cancer Of Head And Neck

Squamous Cell Carcinoma Of Oropharynx Nos

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris LY6D VGNC VGNC:42872
Bos taurus LY6D VGNC VGNC:31088
Rattus norvegicus LY6D RGD RGD:1306132
Mus musculus LY6D MGD MGI:96881
Macaca mulatta LY6D VGNC VGNC:104461
Others LY6D NCBI